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3-NITRO-P-HYDROXYETHYLAMINOPHENOL

CAS 65235-31-6 · 70/100 · High conf.

3-NITRO-P-HYDROXYETHYLAMINOPHENOL chemical structure

Concern score

70/100High concern based on regulatory listings.
High confidence

3-NITRO-P-HYDROXYETHYLAMINOPHENOL in plain language

What it is

Also known as 3-NITRO-4-N-(.BETA.-HYDROXYETHYL)AMINOPHENOL · 4-(2-hydroxyethylamino)-3-nitrophenol · HYDROXYETHYL-AMINO-3-NITROPHENOL, 4-N-BETA- · 3-NITRO-4-.BETA.-HYDROXYETHYLAMINOPHENOL · 3-NITRO-P- hydroxyethylamin ophenol · 3-nitro-p- hydroxyethylaminoph enol

Show all 14 names

4-(2-hydroxyethylamino)-3-nitro-phenol · Colorex red 54 · Hc red B54 · Imexine fh · Jarocol nheap · N-(2-Hydroxyethyl) 4-hydroxy-2-nitroaniline · Rodol henp · UNII-AIP2J155AN

What it does

Used in cosmetics as a hair dye.

  • Hair dyeing
  • Colourant
Is it a concern?
High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

4-[(2-Hydroxyethyl)amino-3-nitrophenol is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex III — restricted
  • EU restricted in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • EUEC

    Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: (a) Hair dye substance in oxidative hair dye products (b) Hair dye substance in non-oxidative hair dye products Maximum concentration: (b) 1.85 % Other conditions: (a) After mixing under oxidative conditions themaximum concentration applied to hair must not exceed 3.0% For (a) and (b): - Do not use with nitrosating agents - Maximum nitrosamine content: 50 microgram/Kg - Keep in nitrite-free containers Conditions of use and warnings: For (a) and (b): Hair colourants can use severe allergic reactions Read and follow intructions

    restricted
    View source →
  • EUCosIngActive2 entries
  • USEPAcommercial use observedEPA CPDat observed this chemical in 7 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Dye.
    • EPA CPDat observed this chemical in 7 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Dye.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 3-NITRO-P-HYDROXYETHYLAMINOPHENOL. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 3-NITRO-P-HYDROXYETHYLAMINOPHENOL yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2013-07-26

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 3-NITRO-P-HYDROXYETHYLAMINOPHENOL in a product composition. These are source records, not Greenveil catalog products.

Source records

7

Named organisations

5

Personal care

Typical roles

Hair dyeingColourant
See products using 3-NITRO-P-HYDROXYETHYLAMINOPHENOL →

Catalog

Found in these products

Cosmetic and personal-care products that list 3-NITRO-P-HYDROXYETHYLAMINOPHENOL are shown first. Their ingredient lists include 3-NITRO-P-HYDROXYETHYLAMINOPHENOL; each product's own rating depends on its whole formula, so it is shown on the product page, not here.