# PIGMENT RED 112

URL: https://app.greenveil.ai/ingredients/ingredient_cas_6535_46_2
Categories: beauty, industrial
Functions: Colorant, Hair dyeing, Colourant
Identifier: 6535-46-2

> PIGMENT RED 112: Used in cosmetics as a colourant and a hair dye. CI 12370 is classed chemically as a monoazo colour. Greenveil chemical-concern score: 100/100 — Critical concern based on regulatory listings.. Compiled from 6 published data sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern based on regulatory listings.
- Confidence in this assessment: High
- Is it a concern? Critical concern: no hazard classifications on record. It is banned in EU cosmetics.
- Rationale: 3-Hydroxy-N-(o-tolyl)-4-[(2,4,5-trichlorophenyl)azo]naphthalene-2-carboxamide (Pigment Red 112; CI 12370) and its salts when used as a substance in hair dye products is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: Active — Cosmetics Regulation annex IV / ref 11.
- EU: Active — Cosmetics Regulation annex II / ref 1346.
- EU: Active — CI 12370 is classed chemically as a monoazo colour. It conforms to the formula: Restriction: IV/11 (CI 12370)
II/1346 (Pigment Red 112; CI 12370: and its salts when used as a substance in hair dye products)
- EU: Active — Pigment Red 112 is classed chemically as a monoazo colour. It conforms to the formula: Restriction: II/1346 (Pigment Red 112; CI 12370: and its salts when used as a substance in hair dye products)
- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
- EU: allowed_listed — Annex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Maximum concentration: Rinse-off products
- US: commercial use observed — EPA CPDat observed this chemical in 10 composition records across product categories including Specialty occupational products, Electronics/small appliances. EPA CPDat classifies this chemical for functional uses including Dye, Pigment.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

## Expert safety opinions

- SCCS (EU Scientific Committee on Consumer Safety): no opinion on file.
- CIR (Cosmetic Ingredient Review (US expert panel)): no opinion on file.

## Data sources

- CosIng (updated 2026-09-23): https://ec.europa.eu/growth/tools-databases/cosing/details/30395
- EU CosIng Cosmetics Regulation Annexes (updated 2020-08-13): https://ec.europa.eu/growth/tools-databases/cosing/reference/annexes/list/II
- EPA Chemical and Products Database (updated 2020-02-13): http://siri.org/msds/f2/ccw/ccwsl.html
- EPA DSSTox Identifiers (updated 2025-12-29): https://epa.figshare.com/articles/dataset/Chemistry_Dashboard_Data_DSSTox_Identifiers_Mapped_to_CAS_Numbers_and_Names/5588566
- FDA GSRS UNII (updated 2026-02-26): https://precision.fda.gov/uniisearch/
- openFDA Substance (updated 2026-05-24): https://api.fda.gov/other/substance.json?search=unii:6S30UYY7FD

_Assessed by Greenveil._