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POLYGLYCERYL-2 diisostearate

CAS 63705-03-3

Also registered as 4 other CAS numbers

78637-02-2 · 85005-50-1 · 1228753-09-0 · 67938-21-0

POLYGLYCERYL-2 diisostearate chemical structure

Concern score

Not assessed — no hazard data yet.

POLYGLYCERYL-2 diisostearate in plain language

What it is

On cosmetic ingredient lists it appears as “POLYGLYCERYL-2 sesquiisostearate”.

Also known as POLYGLYCERYL-2 sesquiisostearate · Di(isooctadecanoic) acid, diester with oxydi(propanedio · Aec POLYGLYCERYL-2 diisostearate · Diglycerin diisostearate · Diglyceryl diisostearate · Isooctadecanoic acid, diester with oxybis(propanediol)

Show all 21 names

Cithrol pg 22IS · Cosmol 42V · Dermol dgdis · Di(isooctadecanoic) acid, diester with oxydi(propanediol) · Ec 267-821-6 · Isooctadecanoic acid, diester with diglycerol · Isooctadecanoic acid, diester with oxybis(propenediol) · Isooctadecanoic acid, diester with oxybispropanediol · Isooctadecanoic acid, diester with oxydi(propanediol) · Matsunate di · Matsunate MI-220 · Risorex PGIS22 · S-face IS-202 p · Salacos 42V · Sunsoft Q-192B

What it does

Used in cosmetics as an emulsifier. Diester of diglycerol and isostearic acid.

  • Emulsifying
  • Emulsifier
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. POLYGLYCERYL-2 diisostearate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActive2 entries
    • Diester of diglycerol and isostearic acidSource →
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observed2 entries
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Emulsifier.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for POLYGLYCERYL-2 diisostearate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for POLYGLYCERYL-2 diisostearate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated 2019-03-06

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed POLYGLYCERYL-2 diisostearate in a product composition. These are source records, not Greenveil catalog products.

Named organisations

1

Typical roles

EmulsifyingEmulsifier
See products using POLYGLYCERYL-2 diisostearate →

Catalog

Found in these products

Cosmetic and personal-care products that list POLYGLYCERYL-2 diisostearate are shown first. Their ingredient lists include POLYGLYCERYL-2 diisostearate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 23 →Find products without it →