- beauty
- cleaning
- industrial
- pharma
Pentetic acid
CAS 67-43-6 · 100/100 · High conf.
Also registered as 10 other CAS numbers
1004765-76-7 · 6889-50-5 · 7575-40-8 · 13407-13-1 · 25737-54-6 · 49758-21-6 · 84932-15-0 · 573987-64-1 · 782415-12-7 · 803683-39-8
Concern score
100/100Critical concern based on regulatory listings.
High confidence
Pentetic acid in plain language
Also known as Diethylenetriamine pentaacetic acid · Pentetate · Diethylenetriaminepentaacetic acid · Diethylene triamine pentaacetic acid · Diethylenetriamine- n,n,n',n',n''-pentaacetic acid · Diethylenetriaminepentaacetate
Show all 38 names
(Diethylenetrinitrilo)pentaacetic acid · 1,1,4,7,7-Diethylenetriaminepentaacetic acid · 3,6,9-Triazaundecanedioic acid, 3,6,9-tris(carboxymethyl)- · Acide pentetique · Acido pentetico · Acidum penteticum · Carboxymethyliminobis(ethylenenitrilo) tetraacetic acid · CHEL 330 acid · Chel DTPA · Dtp-a · Dabeersen 503 · Detapac · Detarex · Diethylenetriamine-N,N,N',N'',N''-pentaacetic acid · Dissolvine D · Monaquest CAI · N-Carboxymethyliminobis(ethylenenitrilo)tetra(acetic acid) · Nanodtpa · Pentacarboxymethyldiethylenetriamine · Penthamil · Penthanil · Perma kleer · Titriplex V · acide N-carboxymethyliminobis(ethylenenitrilo)tetraacetique · acido N-carboximetiliminobis(etilennitrilo)tetraacetico · diethylenetriaminepentaacetic acid na5 · diethylenetriaminepentaacitic acid · diethylenetriaminepentaacitic acid/pentetic acid · dtpa · Nano-dtpa capsule component dtpa · Nanodtpa component dtpa · Nanodtpa zn-dtpa component dtpa
Used in cosmetics as a chelating agent. Pentetic Acid is the substituted amine.
- Chelating
- Chelating agent
- Cleaning agent
- Critical concern: no hazard classifications on record. It is banned in EU cosmetics.
Why it's flagged
N-carboxymethyliminobis(ethylenenitrilo)tetra(acetic acid); Pentetic Acid (INCI) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- In marketed US drugs
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Inactive ingredient in US drugs
- Found in consumer products
- Beauty
- Cleaning
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
USEPAcommercial use observedEPA CPDat observed this chemical in 120 composition records across product categories including Specialty occupational products, Home maintenance, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Chelating agent, Cleaning agent.
- EPA CPDat observed this chemical in 120 composition records across product categories including Specialty occupational products, Home maintenance, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Chelating agent, Cleaning agent.Source →
USFDAinactive ingredient databaseRoute: INTRAVENOUS; Dosage form: INJECTION; Potency: 2 mg
- Route: INTRAVENOUS; Dosage form: INJECTION; Potency: 2 mgSource →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 2 active drug products and 2 total products.
- FDA NDC lists this ingredient in 2 active drug products and 2 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Pentetic acid. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Pentetic acid yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2023-08-24
- Open →
EPA Chemical and Products Database
exposure · updated November 2014
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
- Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Reference links (1)
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
Where it has been recorded
How often EPA CPDat has listed Pentetic acid in a product composition. These are source records, not Greenveil catalog products.
Source records
120
Named organisations
6
Specialty occupational productsHome maintenanceCleaning products and household carePersonal carePet and animal care
Typical roles
ChelatingChelating agentCleaning agent
Found in these products
Cosmetic and personal-care products that list Pentetic acid are shown first. Their ingredient lists include Pentetic acid; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
