Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- food
- industrial
- pharma
Dimethyl sulfoxide
CAS 8070-53-9 · 100/100 · High conf.
Also registered as 4 other CAS numbers
164071-41-4 · 705301-21-9 · 1173018-42-2 · 67-68-5
Concern score
100/100Critical concern based on regulatory listings.
High confidence
Dimethyl sulfoxide in plain language
On cosmetic ingredient lists it appears as “Dmso”.
Also known as Dmso · Methylsulfinylmethane · Dimethyl sulfoxide (INN) · (Methanesulfinyl)methane · Dimethylsulfoxide · Deltan
Show all 28 names
Demasorb · Demavet · Demeso · Demsodrox · Dimethyl Sulphoxide · Dimethylsulfoxid · Dimexide · Dolicur · Domoso · Dromisol · Durasorb · Hyadur · Infiltrina · Methyl sulphoxide · Methane, sulfinylbis- · Methyl sulfoxide · RIMSO-50 · Sq 9453 · Somipront · dimethyl sulfoxide (dmso extract by ip346 from ingred #1) · dimethyl sulfoxide (dmso) · sulfinylbismethane
Used in cosmetics as a solvent.
- Solvent
- Fragrance
- Flavouring
- Critical concern: no hazard classifications on record. It is banned in EU cosmetics.
Why it's flagged
Dimethyl sulfoxide (INN) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- In marketed US drugs
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Inactive ingredient in US drugs
- Found in consumer products
- Beauty
- Pharma
- Food
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
USFDAinactive ingredient database4 entries — 3 administration routes
USEPAcommercial use observedEPA CPDat observed this chemical in 82 composition records across product categories including Construction and building materials, Laboratory supplies, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including Solvent, Flavouring and nutrient, carrier for rheology.
- EPA CPDat observed this chemical in 82 composition records across product categories including Construction and building materials, Laboratory supplies, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including Solvent, Flavouring and nutrient, carrier for rheology.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 1 active drug products and 1 total products.
- FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Dimethyl sulfoxide. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Dimethyl sulfoxide yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2010-10-27
- Open →
EPA Chemical and Products Database
exposure · updated jan 24 1989
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
- Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Allergen profile
Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.
- SoyContains · Oral (ingested)
Source: chemindex_name_match
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
Where it has been recorded
How often EPA CPDat has listed Dimethyl sulfoxide in a product composition. These are source records, not Greenveil catalog products.
Source records
82
Named organisations
6
Construction and building materialsLaboratory suppliesSpecialty occupational productsPersonal careRaw materialsFood and drug
Typical roles
SolventFragranceFlavouring
Found in these products
Their ingredient lists include Dimethyl sulfoxide; each product's own rating depends on its whole formula, so it is shown on the product page, not here.
