# DIMETHYL SULFOXIDE

URL: https://app.greenveil.ai/ingredients/ingredient_cas_67_68_5
Categories: beauty, food, industrial, pharma
Functions: carrier for rheology, Flavouring and nutrient, Fragrance, Solvent
Identifier: 67-68-5

> DIMETHYL SULFOXIDE is used as carrier for rheology / flavouring and nutrient. Greenveil chemical-concern score: 100/100 — Critical concern based on regulatory listings.. Assessed from 11 sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern based on regulatory listings.
- Confidence: 4
- Rationale: Dimethyl sulfoxide (INN) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
- US: commercial use observed — EPA CPDat observed this chemical in 82 composition records across product categories including Construction and building materials, Laboratory supplies, Specialty occupational products. EPA CPDat classifies this chemical for functional uses including Solvent, Flavouring and nutrient, carrier for rheology.
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Potency: NA
- US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: IMPLANT; Potency: 104 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: LOTION; Potency: 45.5 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SOLUTION; Maximum daily exposure: 8008 mg
- US: marketed drug occurrence — FDA NDC lists this ingredient in 1 active drug products and 1 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._