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Hexachlorophene

CAS 70-30-4 · 100/100 · High conf.

Also registered as 3 other CAS numbers

8054-98-6 · 139411-96-4 · 1195388-85-2

Hexachlorophene chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Hexachlorophene in plain language

What it is

Also known as 2,2'-Methylenebis(3,4,6-trichlorophenol) · Hexachlorophane · 2,2',3,3',5,5'-Hexachloro-6,6'-dihydroxydiphenylmethane · 2,2'-Dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane · 2,2'-Dihydroxy-3,5,6,3',5',6'-hexachlorodiphenylmethane · 2,2'-Methylene bis(3,4,6-trichlorophenol)

Show all 38 names

Acigena · Almederm · Dial · Dermadex · Distodin · E-z scrub · Exofene · Fostril · Gamophen · Germa-medica · Gamophene · Hexa-germ · Hexascrub · Hexabalm · Hexachlorofen · Hexophene · Nabac · Phiso-scrub · Phisohex · Pre-op · Phisodan · Scrubteam surgical spongebrush · Septi-soft · Septisol · Soy-dome · Septofen · Steraskin · Surofene · Turgex · hexachlorophen · hexachlorophene (sara 313) (cercla) · hexachlorophene (sara iii)

What it does

Used in cosmetics as a preservative.

  • Preservative
Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

2,2'-Dihydroxy-3,3',5,5',6,6'-hexachlorodiphenylmethane (Hexachlorophene (INN)) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • In marketed US drugs
  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActive2 entries
  • USEPAcommercial use observedEPA CPDat observed this chemical in 23 composition records across product categories including Cleaning and safety, Arts and crafts/office supplies, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Preservative.
    • EPA CPDat observed this chemical in 23 composition records across product categories including Cleaning and safety, Arts and crafts/office supplies, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Preservative.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 1 active drug products and 1 total products.
    • FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Hexachlorophene. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Hexachlorophene yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-20

    Open →
  • EPA Chemical and Products Database

    exposure · updated 4 December 2007

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Hexachlorophene in a product composition. These are source records, not Greenveil catalog products.

Source records

23

Named organisations

6

Cleaning and safetyArts and crafts/office suppliesLaboratory suppliesCleaning products and household careFood and drug

Typical roles

Preservative
See products using Hexachlorophene →