beauty
industrial
pharma

Stannous fluoride

CAS 12324-56-0 · 70/100 · High conf.

Also registered as 2 other CAS numbers

12324-60-6 · 7783-47-3

Concern score

70/100High concern based on regulatory listings.

High confidence

Stannous fluoride in plain language

What it is: Also known as Cid 134688170 · Tin fluoride (SnF2) · difluorostannane · Difluorostannylene · Difluorure d'etain · Fluoristan
Show all 12 names
Gel-Tin · Tin (II) fluoride · Tin difluoride · Tin fluoride, · difluoruro de estano · stannous flouride
What it does: Used in cosmetics as an antiplaque and an oral-care ingredient.
Antiplaque
Oral care
Is it a concern?: High concern: no hazard classifications on record. It is restricted in EU cosmetics.

Why it's flagged

Stannous Fluoride is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

In marketed US drugs
EU Annex III — restricted
EU restricted in cosmetics
Inactive ingredient in US drugs

Recorded in these product areas

Found in consumer products
Beauty
Industrial

EUEC
Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: Oral products Maximum concentration: 0,15 % calculated as F. When mixed with other fluorine compounds permitted under this Annex, total F concentration must not exceed 0,15 % Conditions of use and warnings: Contains stannous fluoride For any toothpaste with compounds containing fluorine in a concentration of 0.1 to 0.15% calculated as F unless it is already labelled as contra-indicated for children (e.g. "for adult use only") the following labelling is obligatory: "Children of 6 years and younger: use a pea-sized amount for supervised brushing to minimise swallowing. In case of intake of fluoride…
restricted
View source →

EUCosIngActive2 entries
- Restriction: III/35Source →
- Cosmetics Regulation annex III / ref 35.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 54 composition records across product categories including Medical/dental, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including oral care, Pharmaceutical, Oral Care Agent.
- EPA CPDat observed this chemical in 54 composition records across product categories including Medical/dental, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including oral care, Pharmaceutical, Oral Care Agent.Source →
USFDAinactive ingredient databaseRoute: INTRAVENOUS; Dosage form: INJECTION; Potency: 0.73 mg
- Route: INTRAVENOUS; Dosage form: INJECTION; Potency: 0.73 mgSource →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 157 active drug products and 175 total products.
- FDA NDC lists this ingredient in 157 active drug products and 175 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Stannous fluoride. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Stannous fluoride yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2013-05-14
Open →
EPA Chemical and Products Database
exposure · updated July 2019
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA Inactive Ingredient Database
regulatory · updated 2026-01-09
Open →
FDA National Drug Code Directory
regulatory · updated 2028-08-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Stannous fluoride in a product composition. These are source records, not Greenveil catalog products.

Source records

175

Typical roles

AntiplaqueOral care

See products using Stannous fluoride →

Catalog

Found in these products

Their ingredient lists include Stannous fluoride; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 92 →Find products without it →