Fragrance avoidance
No fragrance-linked caution surfaced in the current profile.
This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.
- beauty
- industrial
Dimethyl sulfate
CAS 77-78-1 · 100/100 · High conf.
Also registered as 5 other CAS numbers
286013-18-1 · 1216599-58-4 · 62086-97-9 · 98478-67-2 · 139443-72-4
Concern score
100/100Critical concern driven by cmr.
High confidence
Dimethyl sulfate in plain language
Also known as Dimethyl sulphate · Dimethyl ester sulfuric acid · Dimethylsulfate · DMS (methyl sulfate) · Dimethyl monosulfate · Dimethylester kyseliny sirove
Show all 17 names
Dimethylsulfaat · Dimethylsulfat · Dimetilsolfato · Dwumetylowy siarczan · Methyle (sulfate de) · RCRA waste number U103 · Sulfate de dimethyle · Sulfate de methyle · Sulfate dimethylique · dimethyl sulfate (sara iii) · sulfato de dimetilo
We don't have a plain-language description for Dimethyl sulfate yet.
- Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.
Why it's flagged
- Cmr
Dimethyl sulphate is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.
RestrictedEU EC — banned
The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.
Regulation
Restrictions first, then routine listings from published regulatory sources.
- EU Annex II — prohibited
- EU prohibited in cosmetics
- Found in consumer products
- Industrial
- View source →banned
EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 1B(C=>0.01%),Mutagenic Cat. 2(C=>0.01%)
EUCosIngActiveCosmetics Regulation annex II / ref 750.
- Cosmetics Regulation annex II / ref 750.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 6 composition records across product categories including Laboratory supplies, Specialty occupational products.
- EPA CPDat observed this chemical in 6 composition records across product categories including Laboratory supplies, Specialty occupational products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Expert safety opinions
No expert opinion on file for Dimethyl sulfate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.
SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
Evidence & sources
No graded research studies for Dimethyl sulfate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.
Where this comes from
- Open →
CosIng
regulatory · updated 2026-09-23
- Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2010-10-15
- Open →
EPA Chemical and Products Database
exposure · updated jan 24 1989
- Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
- Open →
FDA GSRS UNII
registry · updated 2026-02-26
- Open →
openFDA Substance
registry · updated 2026-05-24
- Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Where it has been recorded
How often EPA CPDat has listed Dimethyl sulfate in a product composition. These are source records, not Greenveil catalog products.
Source records
6
Named organisations
5
Laboratory suppliesSpecialty occupational products
See products using Dimethyl sulfate →