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GREENVEIL

  • beauty
  • industrial

RH-POLYPEPTIDE-16

CAS 797794-90-2

Concern score

Not assessed — no hazard data yet.

RH-POLYPEPTIDE-16 in plain language

What it does

Used in cosmetics as a skin-conditioning agent.

  • Skin conditioning
  • Conditioner
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. RH-POLYPEPTIDE-16 appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActiverh-Polypeptide-16 is a homodimeric, recombinant, non-glycosylated, peptide, produced using the human gene for Placental Growth Factor-1 containing a one base mutation by fermentation in E. coli. This oligopeptide contains 125 amino acids and is composed of: methionine, leucine, proline, alanine, valine, glutamine, tryptophan, serine, glycine, glycine, asparagine, glutamic acid, phenylalanine, arginine, tyrosine, cysteine, aspartic acid, histidine, threonine, lysine, isoleucine Restriction: II/416
    • rh-Polypeptide-16 is a homodimeric, recombinant, non-glycosylated, peptide, produced using the human gene for Placental Growth Factor-1 containing a one base mutation by fermentation in E. coli. This oligopeptide contains 125 amino acids and is composed of: methionine, leucine, proline, alanine, valine, glutamine, tryptophan, serine, glycine, glycine, asparagine, glutamic acid, phenylalanine, arginine, tyrosine, cysteine, aspartic acid, histidine, threonine, lysine, isoleucine Restriction: II/416Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Softener and conditioner.Source →

Expert safety opinions

No expert opinion on file for RH-POLYPEPTIDE-16. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for RH-POLYPEPTIDE-16 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

2 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated 2019-12-31

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed RH-POLYPEPTIDE-16 in a product composition. These are source records, not Greenveil catalog products.

Named organisations

1

Typical roles

Skin conditioningConditioner
See products using RH-POLYPEPTIDE-16 →