beauty
food
pharma

1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline

CAS 8003-22-3 · 100/100 · High conf.

Also registered as 1 other CAS number

83-08-9

1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline chemical structure

Concern score

100/100Critical concern based on regulatory listings.

High confidence

1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline in plain language

What it is: On cosmetic ingredient lists it appears as “CI 47000”.
Also known as CI 47000 · CI 47000 / solvent yellow 33 · Solvent yellow 33 · Yellow 11 · Quinoline Yellow · Quinophthalone
Show all 23 names
2-(Quinolin-2-yl)-1H-indene-1,3(2H)-dione · 2-quinolin-2-ylindene-1,3-dione · 11641 Yellow · 1H-Indene-1,3(2H)-dione, 2-(2-quinolinyl)- · 2-(2-Quinolinyl)-1H-indene-1,3(2H)-dione · 2-(2-Quinolyl)-1,3-indandione · 2-(2-Quinolyl)-1,3-indanedione · 2-(2-Quinolyl)-1H-indene-1,3(2H)-dione · 2-Quinolin-2-yl-indane-1,3-dione · C.I. solvent yellow 33 · Colour Index No. 47005 · D & C Yellow 11 · D&C Yellow No 10 · D.C. Yellow No. 10 · Erio Chinoline Yellow 4G · Quinoline Yellow 2SF · d&c yellow no. 11
What it does: Used in cosmetics as a colourant and a hair dye. CI 47000 is classed chemically as a quinoline colour.
Colorant
Hair dyeing
Colourant
Is it a concern?: Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline (Solvent Yellow 33; CI 47000) when used as a substance in hair dye products is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

EU Annex II — prohibited
EU Annex IV — permitted colorant
EU permitted colorant
EU prohibited in cosmetics

Recorded in these product areas

Found in consumer products
Beauty
Pharma
Food

EUEC
Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
banned
View source →

EUCosIngActive5 entries
- Cosmetics Regulation annex IV / ref 81.Source →
- Cosmetics Regulation annex II / ref 1358.Source →
- CI 47000 is classed chemically as a quinoline colour. It conforms to the formula: Restriction: IV/81 (CI 47000) (colorant) II/1358 (Solvent Yellow 33; CI 47000: when used as a substance in hair dye products)Source →
- 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline (CI 47000) Restriction: IV/81 (CI 47000) (colorant) II/1358 (Solvent Yellow 33; CI 47000: when used as a substance in hair dye products)Source →
- Listed in CosIng inventory for cosmetic use.Source →
EUECallowed_listedAnnex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Maximum concentration: Not to be used in products applied on mucous membranes
- Annex IV of EU Cosmetics Regulation (EC) 1223/2009: colorants allowed in cosmetic products. Maximum concentration: Not to be used in products applied on mucous membranesSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 3 composition records across product categories including Food and drug, Personal care. EPA CPDat classifies this chemical for functional uses including Dye, Pigment.
- EPA CPDat observed this chemical in 3 composition records across product categories including Food and drug, Personal care. EPA CPDat classifies this chemical for functional uses including Dye, Pigment.Source →

Expert safety opinions

No expert opinion on file for 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EU CosIng Cosmetics Regulation Annexes
regulatory · updated 2013-05-08
Open →
EPA Chemical and Products Database
exposure · updated june 26, 2013
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline in a product composition. These are source records, not Greenveil catalog products.

Source records

Named organisations

Food and drugPersonal care

Typical roles

ColorantHair dyeingColourant

See products using 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline →

Catalog

Found in these products

Their ingredient lists include 1,3-Isobenzofurandione, reaction products with methylquinoline and quinoline; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 32 →Find products without it →