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Bisphenol a

CAS 27360-89-0 · 100/100 · High conf.

Also registered as 6 other CAS numbers

28106-82-3 · 37808-08-5 · 137885-53-1 · 146479-75-6 · 1429425-26-2 · 80-05-7

Bisphenol a chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

Bisphenol a in plain language

What it is

On cosmetic ingredient lists it appears as “4'-ISOPROPYLIDENEDIPHENOL”.

Also known as 4'-ISOPROPYLIDENEDIPHENOL · 4,4'-ISOPROPYLIDENEDIPHENOL · Bisphenol A (4,4'-Isopropylidenediphenol) · (4,4'-Dihydroxydiphenyl)dimethylmethane · 2,2'-Bis(4-hydroxyphenyl)propane · 2,2-BIS(4-HYDROXYPHENYL)PROPANE

Show all 15 names

2,2-BIS-(4-HYDROXY-PHENYL)-PROPANE · 2,2-Bis(4'-hydroxyphenyl) propane · 4,4'-(1-METHYLETHYLIDENE)BISPHENOL · 4,4'-(Propane-2,2-diyl)diphenol · 4,4'-Propane-2,2-diyldiphenol · 4,4’-Propane-2,2-diyldiphenol · Brass Metal Flake · Phenol, 4,4'-(1-methylethylidene)bis- · bisphenol a (sara 313)

What it does

Used in cosmetics as an antioxidant.

  • Antioxidant
Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

Bisphenol A (4,4'-Isopropylidenediphenol) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • In marketed US drugs
  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Pharma
  • Food
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Reprotoxic Cat. 1B()

    banned
    View source →
  • EUCosIngActive2 entries
    • Cosmetics Regulation annex II / ref 1176.Source →
    • 4,4'-(1-Methylethylidene)Bisphenol Restriction: II/1176 CMR 1BSource →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 295 composition records across product categories including Furniture and furnishings, Raw materials, Medical/dental. EPA CPDat classifies this chemical for functional uses including No specific technical function, Binder, Hardener.
    • EPA CPDat observed this chemical in 295 composition records across product categories including Furniture and furnishings, Raw materials, Medical/dental. EPA CPDat classifies this chemical for functional uses including No specific technical function, Binder, Hardener.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 7 active drug products and 13 total products.
    • FDA NDC lists this ingredient in 7 active drug products and 13 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Bisphenol a. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Bisphenol a yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2018-04-24

    Open →
  • EPA Chemical and Products Database

    exposure · updated february 2, 2017

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2029-06-12

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Bisphenol a in a product composition. These are source records, not Greenveil catalog products.

Source records

295

Named organisations

6

Furniture and furnishingsRaw materialsMedical/dentalHome maintenanceConstructionFood and drug

Typical roles

Antioxidant
See products using Bisphenol a →