Musk ketone

Musk ketone in plain language

What it is

Also known as 4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone · 1-(4-tert-Butyl-2,6-dimethyl-3,5-dinitrophenyl)ethan-1-one · 1-(4-tert-butyl-2,6-dimethyl-3,5-dinitrophenyl)ethanone · 2,6 DIMETHYL-4-TERT-BUTYL-3,5-DINITROACETOPHENONE · 2,6-DIMETHYL-3,5-DINITRO-4-TERT-BUTYL acetophenone · 3,5-DINITRO-2,6-DIMETHYL-4-TERT-BUTYLACETOPHENONE

Show all 18 names

3,5-DINITRO-4-TERT-BUTYL-2,6-DIMETHYLACETOPHENONE · 4-ACETO-3,5-DIMETHYL-2,6-DINITRO-TERT-BUTYLBENZENE · 4-TERT-BUTYL-2,6-DIMETHYL-3,5-DINITROACETOPHENONE · 1-TERT-BUTYL-3,5-DIMETHYL-2,6-DINITRO-4-ACETYLBENZENE · 2,6-Dimethyl-3,5-dinitro-4-t-butylacetophenone · 2,6-Dinitro-3,5-dimethyl-4-acetyl-tert-butylbenzene · 2-Acetyl-5-tert-butyl-4,6-dinitroxylene · 4-tert-Butyl-3,5-dinitro-2,6-dimethylacetophenone · Acetophenone, 4'-tert-butyl-2',6'-dimethyl-3',5'-dinitro- · Ketone moschus · Ketone musk · butyl-2',6'-dimethyl-3',5'-dinitroacetophenone

What it does

Used in cosmetics as a fragrance ingredient.

• Perfuming
• Fragrance
• Flavouring
• Deodorant

Is it a concern?

High concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is restricted in EU cosmetics.

Why it's flagged

• Cmr

4'-tert-Butyl-2',6'-dimethyl-3',5'-dinitroacetophenone is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• EU Annex III — restricted
• EU restricted in cosmetics

• EU·EC

  Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: All cosmetic products, with the exception of oral care products Maximum concentration: (a) 1.4% in fine fragrance (b) 0.56% in eau de toilette (c) 0.042% in other products CMR: Carcinogenic Cat. 2()

  restricted
  View source →

• EU·CosIng·Active2 entries

  • Cosmetics Regulation annex III / ref 97.Source →
  • Restriction: III/97Source →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 6 composition records across product categories including Cleaning products and household care, Vehicle, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Deodorizer, Fragrance, Flavouring and nutrient.

  • EPA CPDat observed this chemical in 6 composition records across product categories including Cleaning products and household care, Vehicle, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Deodorizer, Fragrance, Flavouring and nutrient.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Musk ketone. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.