Musk xylene

Musk xylene in plain language

What it is

Also known as 5-tert-Butyl-2,4,6-trinitro-m-xylene · 1-tert-Butyl-3,5-dimethyl-2,4,6-trinitrobenzene · Moschus xylol · Musk xylol · Xylene musk · 1-(1,1-Dimethylethyl)-3,5-dimethyl-2,4,6-trinitrobenzene

Show all 15 names

1-tert-butyl-3,5-dimethyl-2,4,6-trinitro-benzene · 2,4,6-TRINITRO-3,5-DIMETHYL-1-TERT-BUTYLBENZENE · 2,4,6-Trinitro-1,3-dimethyl-5-tert-butylbenzene · 2,4,6-Trinitro-3,5-dimethyl-tert-butylbenzene · 2,4,6-Trinitro-5-tert-butyl-m-xylene · 5-TERT-BUTYL-2,4,6-TRINITROXYLENE · Benzene, 1-TERT-BUTYL-3,5-DIMETHYL-2,4,6-TRINITRO- · Benzene, 1-(1,1-dimethylethyl)-3,5-dimethyl-2,4,6-trinitro- · m-Xylene, 5-tert-butyl-2,4,6-trinitro-

What it does

Used in cosmetics as a fragrance ingredient.

• Perfuming
• Fragrance
• Deodorant

Is it a concern?

High concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is restricted in EU cosmetics.

Why it's flagged

• Cmr

5-tert-Butyl-2,4,6-trinitro-m-xylene is restricted in cosmetic products under Annex III of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — restricted

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• In marketed US drugs
• EU Annex III — restricted
• EU restricted in cosmetics

• EU·EC

  Annex III of EU Cosmetics Regulation (EC) 1223/2009: substances which cosmetic products must not contain except subject to the restrictions laid down. Product types: All cosmetic products, with the exception of oral products Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’ Maximum concentration: (a) 1.0% in fine fragrance (b) 0.4% in eau de toilette (c) 0.03% in other products CMR: Carcinogenic Cat. 2()

  restricted
  View source →

• EU·CosIng·Active2 entries

  • Cosmetics Regulation annex III / ref 96.Source →
  • Restriction: III/96 Note: 'Due to environmental concerns, musk xylene is included in the authorisation list (Annex IV) of REACH. Musk xylene cannot be placed on the market or used unless authorisation has been granted under REACH’.Source →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Deodorizer, Fragrance.

  • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Deodorizer, Fragrance.Source →
• US·FDA·marketed drug occurrenceFDA NDC lists this ingredient in 1 active drug products and 1 total products.

  • FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Musk xylene. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.