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Warfarin

CAS 81-81-2 · 100/100 · High conf.

Also registered as 4 other CAS numbers

56645-46-6 · 951658-59-6 · 5543-56-6 · 56573-89-8

Warfarin chemical structure

Concern score

100/100Critical concern driven by cmr.
High confidence

Warfarin in plain language

What it is

Also known as Warfarin (INN) and its salts · 4-Hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one · 4-hydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one · (±)-4-HYDROXY-3-(3-OXO-1-PHENYLBUTYL)-2H-1-BENZOPYRAN-2-ONE · 2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl) · 4-HYDROXY-3-((1RS)-3-OXO-1-PHENYLBUTYL)COUMARIN

Show all 36 names

Brumolin · Choice · Circuvit · Co-Rax · Coumadin · Coumafen · Coumafene · Coumarins · Coumefene · Dethmor · Dethnel · Kumader · Kumadu · Kumatox · Kypfarin · Martefarin · Maveran · Ratron · Rodafarin · Rodex · Rosex · Solfarin · Temus W · Vampirinip II · Warf 5 · Warfarine · Zoocoumarin · warfarin (aka coumaphene) · warfarin (sara iii) · warfarin c19h16o4

What it does

We don't have a plain-language description for Warfarin yet.

Is it a concern?
Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

  • Cmr

Warfarin (INN) and its salts is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Pharma
  • Food
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Reprotoxic Cat. 1A()

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 203.
    • Cosmetics Regulation annex II / ref 203.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 9 composition records across product categories including Pesticides, Laboratory supplies, Food and drug.
    • EPA CPDat observed this chemical in 9 composition records across product categories including Pesticides, Laboratory supplies, Food and drug.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Warfarin. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    No JECFA evaluation on file.

  • EFSA

    European Food Safety Authority

    No EFSA opinion on file.

Evidence & sources

No graded research studies for Warfarin yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-20

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2001

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (3)
Openfda substance

accessdata.fda.gov

Openfda substance

clinicalkey.com

Openfda substance

online.lexi.com

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Warfarin in a product composition. These are source records, not Greenveil catalog products.

Source records

9

Named organisations

6

PesticidesLaboratory suppliesFood and drug
See products using Warfarin →