Methylpyrrolidone

Methylpyrrolidone in plain language

What it is

On cosmetic ingredient lists it appears as “Methyl pyrrolidone”.

Also known as Methyl pyrrolidone · N-methylpyrrolidone · 1-METHYL-2-PYRROLIDINONE · 1-METHYLPYRROLIDONE · N-Methyl-2-pyrrolidone · N-Methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone

Show all 24 names

1-Methylpyrrolidin-2-one · Nmp · 1-METHYLPYRROLIDINONE · 1-Methyl-2-pyrrolidon · 1-Methyl-2-pyrrolidone · 1-Methyl-5-pyrrolidinone · 1-Methylazacyclopentan-2-one · 1-metil-2-pirrolidona · 2-PYRROLIDINONE, methyl- · 2-Pyrrolidinone, 1-methyl- · Agsolex 1 · Microposit 2001 · N-METHYL-2-PYRROLIDINONE · N-methyl-pyrrolidone · N-Methyl-alpha-pyrrolidinone · N-Methyl-alpha-pyrrolidone · N-Methyl-gamma-butyrolactam · N-Methylpyrrolidinone

What it does

Used in cosmetics as a solvent. Methyl Pyrrolidone is the substituted heterocyclic organic compound.

• Solvent
• Film former

Is it a concern?

Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

• Cmr

N-Methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• EU Annex II — prohibited
• EU prohibited in cosmetics
• Inactive ingredient in US drugs

• EU·EC

  Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Reprotoxic Cat. 1B()

  banned
  View source →

• US·FDA·inactive ingredient database3 entries — 2 administration routes

  • Route: PERIODONTAL; Dosage form: SYSTEM; Potency: 0.63 mg/mgSource →
  • Route: SUBCUTANEOUS; Dosage form: INJECTION; Maximum daily exposure: 194 mgSource →
  • Route: SUBCUTANEOUS; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 376 mgSource →
• EU·CosIng·Active2 entries

  • Methyl Pyrrolidone is the substituted heterocyclic organic compound that conforms to the formula: Restriction: II/1393Source →
  • Cosmetics Regulation annex II / ref 1393.Source →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 687 composition records across product categories including Raw materials, Vehicle, Industrial products. EPA CPDat classifies this chemical for functional uses including Solvent, Diluent, Binder.

  • EPA CPDat observed this chemical in 687 composition records across product categories including Raw materials, Vehicle, Industrial products. EPA CPDat classifies this chemical for functional uses including Solvent, Diluent, Binder.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Methylpyrrolidone. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.