# METHYLPYRROLIDONE

URL: https://app.greenveil.ai/ingredients/ingredient_cas_872_50_4
Categories: beauty, cleaning, industrial, pharma
Functions: Binder, Diluent, Film former, Flow promoter, Solubility enhancer, Solvent, UV stabilizer
Identifier: 872-50-4

> METHYLPYRROLIDONE is used as binder / diluent. Greenveil chemical-concern score: 100/100 — Critical concern driven by cmr.. Assessed from 9 sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern driven by cmr.
- Confidence: 4
- Rationale: N-Methyl-2-pyrrolidone; 1-methyl-2-pyrrolidone is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Reprotoxic Cat. 1B()
- US: commercial use observed — EPA CPDat observed this chemical in 687 composition records across product categories including Raw materials, Vehicle, Industrial products. EPA CPDat classifies this chemical for functional uses including Solvent, Diluent, Binder.
- US: inactive ingredient database — Route: PERIODONTAL; Dosage form: SYSTEM; Potency: 0.63 mg/mg
- US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION; Maximum daily exposure: 194 mg
- US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 376 mg
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.

_Assessed by Greenveil._