# ISOSORBIDE DINITRATE

URL: https://app.greenveil.ai/ingredients/ingredient_cas_87_33_2
Categories: beauty, food, pharma
Identifier: 87-33-2

> ISOSORBIDE DINITRATE. Greenveil chemical-concern score: 100/100 — Critical concern based on regulatory listings.. Assessed from 8 sources.

## Safety assessment

- Chemical concern score: 100/100 — Critical concern based on regulatory listings.
- Confidence: 4
- Rationale: Isosorbide dinitrate (INN) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

## Regulatory status

- EU: banned — Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.
- US: commercial use observed — EPA CPDat observed this chemical in 5 composition records across product categories including Food and drug.
- US: marketed drug occurrence — FDA NDC lists this ingredient in 61 active drug products and 61 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as concept.

_Assessed by Greenveil._