What does Poloxalene do?

Used in cosmetics as a humectant, an emulsifier and a solvent.

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
cleaning
industrial

Poloxalene

CAS 9003-12-7

Also registered as 115 other CAS numbers

9009-02-3 · 9009-03-4 · 9009-04-5 · 9009-05-6 · 9009-06-7 · 9010-49-5 · 9010-97-3 · 9015-66-1 · 9050-44-6 · 9061-69-2 · 9067-43-0 · 12676-40-3 · 12772-49-5 · 30600-73-8 · 37211-19-1 · 37211-20-4 · 37211-21-5 · 37211-22-6 · 37211-23-7 · 37211-24-8 · 37221-18-4 · 37265-39-7 · 37307-38-3 · 37331-16-1 · 37331-17-2 · 37341-81-4 · 39277-80-0 · 39316-56-8 · 39316-57-9 · 39364-13-1 · 39387-54-7 · 50643-24-8 · 51312-31-3 · 51569-27-8 · 53637-72-2 · 56730-46-2 · 57219-38-2 · 57571-70-7 · 57971-91-2 · 58968-65-3 · +75 more

Concern score

Not assessed — no hazard data yet.

Poloxalene in plain language

What it is: On cosmetic ingredient lists it appears as “Meroxapol 105”.
Also known as Meroxapol 105 · Meroxapol 108 · Meroxapol 171 · Meroxapol 172 · Meroxapol 174 · Meroxapol 178
Show all 88 names
Meroxapol 251 · Meroxapol 252 · Meroxapol 254 · Meroxapol 255 · Meroxapol 258 · Meroxapol 311 · Meroxapol 312 · Meroxapol 314 · PEG-10 propylene glycol · PEG/PPG-2000/200 copolymer · PEG/PPG-205/52 copolymer · Poloxamer 101 · Poloxamer 105 · Poloxamer 108 · Poloxamer 122 · Poloxamer 123 · Poloxamer 124 · Poloxamer 181 · Poloxamer 182 · Poloxamer 183 · Poloxamer 184 · Poloxamer 185 · Poloxamer 188 · Poloxamer 212 · Poloxamer 215 · Poloxamer 217 · Poloxamer 231 · Poloxamer 234 · Poloxamer 235 · Poloxamer 237 · Poloxamer 238 · Poloxamer 282 · Poloxamer 284 · Poloxamer 288 · Poloxamer 331 · Poloxamer 333 · Poloxamer 334 · Poloxamer 335 · Poloxamer 338 · Poloxamer 401 · Poloxamer 402 · Poloxamer 403 · Poloxamer 407 · PEG/PPG-105/5 copolymer · PEG/PPG-116/66 copolymer · PEG/PPG-125/30 copolymer · PEG/PPG-17/6 copolymer · PEG/PPG-18/4 copolymer · PEG/PPG-240/60 copolymer · PEG/PPG-30/160 copolymer · PEG/PPG-35/9 copolymer · meroxapol 108 (methyloxirane-oxirane polymer) · PEG-PPG-105-5 copolymer · PEG-PPG-30-160 copolymer · PEG/PPG-116/66 copolymer (random) · PEG/PPG-125/30 copolymer (random) · PEG/PPG-17/6 copolymer (random) · PEG/PPG-18/4 copolymer (random) · PEG/PPG-240/60 copolymer (random) · PEG/PPG-30/160 copolymer (random) · PEG/PPG-35/9 copolymer (random) · Polyoxyethylene (105) polyoxypropylene (5) glycol · 1,2-Ethanediol, polymer with 1,2-propanediol · 1,2-Propanediol polymer with ethylene oxide · 1,2-Propanediol, polymer with 1,2-ethanediol · 2-Methyl-oxirane polymer with oxirane · Acclaim 2220N · Acclaim 4220N · Actcol ED 56 · Ethylene oxide-propylene oxide copolymer · Oxirane, methyl-, polymer with oxirane · Pepol B-182 · Pepol B-188 · Pluracare l 1220 copolymer · Ucon 75-H-1400 lubricant · Ucon 75-H-450 lubricant · Ucon 75-H-90,000 lubricant · Ucon fluid 75-H-450 · Unilub 75DE-2620R · Unilube 75DE-2620R · nonionic surfactant or polyoxypropylene glycol · polyoxypropylene glycol
What it does: Used in cosmetics as a humectant, an emulsifier and a solvent.
Humectant
Emulsifying
Solvent
Cleansing
Binding
Emulsion stabilising
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Poloxalene appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Cleaning
Industrial

EUCosIngActive49 entries
- Oxirane, methyl-, polymer with oxirane (10;47)Source →
- Oxirane, methyl-, polymer with oxirane (7;91)Source →
- Oxirane, methyl-, polymer with oxirane (12;4)Source →
- Oxirane, methyl-, polymer with oxirane (12;9)Source →
- Oxirane, methyl-, polymer with oxirane (12;23)Source →
- Oxirane, methyl-, polymer with oxirane (12;136)Source →
- Oxirane, methyl-, polymer with oxirane (18;6)Source →
- Oxirane, methyl-, polymer with oxirane (18;14)Source →
- Oxirane, methyl-, polymer with oxirane (18;34)Source →
- Oxirane, methyl-, polymer with oxirane (18;51)Source →
- Oxirane, methyl-, polymer with oxirane (18;163)Source →
- Oxirane, methyl-, polymer with oxirane (21;7)Source →
- Oxirane, methyl-, polymer with oxirane (21;15)Source →
- Oxirane, methyl-, polymer with oxirane (21;39)Source →
- Poly(oxy-1,2-ethanediyl), .alpha, alpha'-1,2-propanediylbis-, omega hydroxy (10 mol EO average molar ratio)Source →
- PEG/PPG-2000/200 Copolymer is a random copolymer produced by the reaction of an average of 2000 moles of ethylene oxide and 200 moles of propylene oxide.Source →
- PEG/PPG-205/52 Copolymer is a random copolymer produced by the interaction of an average of 205 moles of ethylene oxide with 52 moles of propylene oxide.Source →
- Oxirane, methyl-, polymer with oxirane (98;67)Source →
- Oxirane, methyl-, polymer with oxirane (6;67)Source →
- Oxirane, methyl-, polymer with oxirane (13;67)Source →
- Oxirane, methyl-, polymer with oxirane (21;67)Source →
- Oxirane, methyl-, polymer with oxirane (2;16)Source →
- Oxirane, methyl-, polymer with oxirane (11;16)Source →
- Oxirane, methyl-, polymer with oxirane (46;16)Source →
- Oxirane, methyl-, polymer with oxirane (5:21)Source →
- Oxirane, methyl-, polymer with oxirane (7;21)Source →
- Oxirane, methyl-, polymer with oxirane (11;21)Source →
- Oxirane, methyl-, polymer with oxirane (3;30)Source →
- Oxirane, methyl-, polymer with oxirane (8;30)Source →
- Oxirane, methyl-, polymer with oxirane (10;30)Source →
- Oxirane, methyl-, polymer with oxirane (13;30)Source →
- Oxirane, methyl-, polymer with oxirane (19;30)Source →
- Oxirane, methyl-, polymer with oxirane (75;30)Source →
- Oxirane, methyl-, polymer with oxirane (8;35)Source →
- Oxirane, methyl-, polymer with oxirane (24;35)Source →
- Oxirane, methyl-, polymer with oxirane (52;35)Source →
- Oxirane, methyl-, polymer with oxirane (6;39)Source →
- Oxirane, methyl-, polymer with oxirane (22;39)Source →
- Oxirane, methyl-, polymer with oxirane (27;39)Source →
- Oxirane, methyl-, polymer with oxirane (62;39)Source →
- + 9 more entries not shown
USEPAcommercial use observed2 entries
- EPA CPDat observed this chemical in 15 composition records across product categories including Cleaning and safety, Vehicle. EPA CPDat classifies this chemical for functional uses including Cleaning agent.Source →
- EPA CPDat observed this chemical in 218 composition records across product categories including Furniture and furnishings, Home maintenance, Construction and building materials. EPA CPDat classifies this chemical for functional uses including Surfactant (surface active agent), Solvent, Humectant.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as polymer.
- openFDA substance registry classifies this ingredient as polymer.Source →

Expert safety opinions

No expert opinion on file for Poloxalene. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Poloxalene yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated 2020-01-14
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →

Reference links (2)

Openfda substance

dailymed.nlm.nih.gov

Read →

Openfda substance

specialchem4cosmetics.com

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Poloxalene in a product composition. These are source records, not Greenveil catalog products.

Source records

Named organisations

Cleaning and safetyVehicle

Typical roles

HumectantEmulsifyingSolventCleansingBindingEmulsion stabilising

See products using Poloxalene →

Catalog

Found in these products

Cosmetic and personal-care products that list Poloxalene are shown first. Their ingredient lists include Poloxalene; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 403 →Find products without it →