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Tripelennamine

CAS 91-81-6 · 100/100 · High conf.

Tripelennamine chemical structure

Concern score

100/100Critical concern based on regulatory listings.
High confidence

Tripelennamine in plain language

What it is

Also known as Tripelennamine (INN) · N'-benzyl-N,N-dimethyl-N'-pyridin-2-ylethane-1,2-diamine · N,n-dimethyl-n'-benzyl-n'-(.alpha.-pyridyl)ethylenediamine · .BETA.-DIMETHYLAMINOETHYL-2-PYRIDYLAMINOTOLUENE · Benzoxale · Cizaron

Show all 21 names

Ethylenediamine, N-benzyl-N',N'-dimethyl-N-2-pyridyl- · N,N-Dimethyl-N'-benzyl-N'-(α-pyridyl)ethylenediamine · N-BENZYL-N',N'-DIMETHYL-N-(2-PYRIDYL)ETHYLENEDIAMINE · N-BENZYL-N',N'-DIMETHYL-N-PYRIDIN-2-YLETHANE-1,2-DIAMINE · N-Benzyl-N',N'-dimethyl-N-2-pyridylethylenediamine · Piribenzil · Pyribenzamin · Pyrinamine base · Resistamine · Tonaril · Tripelenamina · Tripelennamin · Tripelennamina · Tripelennaminum · beta-Dimethylaminoethyl-2-pyridylbenzylamine

What it does

We don't have a plain-language description for Tripelennamine yet.

Is it a concern?
Critical concern: no hazard classifications on record. It is banned in EU cosmetics.

Why it's flagged

Tripelennamine (INN) is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

Restrictions first, then routine listings from published regulatory sources.

  • In marketed US drugs
  • EU Annex II — prohibited
  • EU prohibited in cosmetics

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUEC

    Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products.

    banned
    View source →
  • EUCosIngActiveCosmetics Regulation annex II / ref 347.
    • Cosmetics Regulation annex II / ref 347.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 3 active drug products and 3 total products.
    • FDA NDC lists this ingredient in 3 active drug products and 3 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Tripelennamine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Tripelennamine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-15

    Open →
  • EPA Chemical and Products Database

    exposure · updated 2020-08-31

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2026-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

en.wikipedia.org

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Tripelennamine in a product composition. These are source records, not Greenveil catalog products.

Source records

3

See products using Tripelennamine →