Benzidine

Benzidine in plain language

What it is

Also known as Benzidine, dyes metabolized to · 4,4′-Diamino-1,1′-biphenyl · 4-(4-aminophenyl)aniline · P-diaminodiphenyl · (1,1'-BIPHENYL)-4,4'-DIAMINE · 4,4'-Bianiline

Show all 32 names

4,4'-Biphenyldiamine · 4,4'-Biphenylenediamine · 4,4'-Diamino-1,1'-biphenyl · 4,4'-Diaminobiphenyl · 4,4'-Diaminodiphenyl · 4,4'-Diphenylenediamine · 4,4′-Bianiline · 4,4′-Biphenyldiamine · 4,4′-Diaminobenzidine · 4,4′-Diaminobiphenyl · 4,4′-Diaminodiphenyl · 4,4′-Diphenylenediamine · Benzidin · Benzidina · Benzioine · Benzydyna · Fast Corinth Base B · NCI-C03361 · benzidine (sara iii) · benzidine. ld50:(oral rat) 309 mg/kg. · biphenyl-4,4'-diamine · p,p'-Bianiline · p,p'-Diaminobiphenyl · p,p'-Dianiline · p,p-Bianiline · C.I. Azoic Diazo Component 112

What it does

Used in consumer products as a colourant.

• Colourant

Is it a concern?

Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

• Cmr

Benzidine is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• EU Annex II — prohibited
• EU prohibited in cosmetics

• EU·EC

  Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 1A(C=>0.01%)

  banned
  View source →

• EU·CosIng·ActiveCosmetics Regulation annex II / ref 26.

  • Cosmetics Regulation annex II / ref 26.Source →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 21 composition records across product categories including Furniture and furnishings, Home maintenance, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Degradant/impurity, Pigment.

  • EPA CPDat observed this chemical in 21 composition records across product categories including Furniture and furnishings, Home maintenance, Laboratory supplies. EPA CPDat classifies this chemical for functional uses including Degradant/impurity, Pigment.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Benzidine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.