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3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate)

CAS 93856-83-8 · 20/100 · High conf.

Also registered as 1 other CAS number

113836-92-3

Concern score

20/100Minor concern based on regulatory listings.
High confidence

3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate) in plain language

What it is

On cosmetic ingredient lists it appears as “Dibromohexamidine isethionate”.

Also known as Dibromohexamidine isethionate · 3,3'-Dibromo-4,4'-hexamethylenedioxydi-benzamidine

What it does

Used in cosmetics as a preservative.

  • Preservative
Is it a concern?
Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

What the listings say

Permitted, with conditions — 3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate) appears on published "allowed" regulatory lists rather than on a restriction list.

3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate) is listed in Annex V of the EU Cosmetics Regulation (EC) 1223/2009 (preservatives allowed in cosmetic products).

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. 3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate) appears in these published regulatory listings.

  • EU Annex V — permitted preservative
  • EU permitted preservative

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActive2 entries
  • EUECallowed_listedAnnex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.1%
    • Annex V of EU Cosmetics Regulation (EC) 1223/2009: preservatives allowed in cosmetic products. Maximum concentration: 0.1%Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Preservative.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Preservative.Source →

Expert safety opinions

No expert opinion on file for 3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate). These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate) yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EU CosIng Cosmetics Regulation Annexes

    regulatory · updated 2010-10-16

    Open →
  • EPA Chemical and Products Database

    exposure · updated 23/01/2020

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed 3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate) in a product composition. These are source records, not Greenveil catalog products.

Named organisations

1

Typical roles

Preservative
See products using 3,3'-Dibromo-4,4'-hexamethylenedioxydibenzamidine and its salts (including isethionate) →