Safrole

Safrole in plain language

What it is

On cosmetic ingredient lists it appears as “Cinnamomum camphora formosana leaf oil rectified”.

Also known as Cinnamomum camphora formosana leaf oil rectified · Cinnamomum camphora formosana root extract · Cinnamomum camphora formosana root oil · Cinnamomum camphora linalooliferum root extract · Cinnamomum camphora linalooliferum root oil · Sassafras officinale bark extract

Show all 37 names

Sassafras officinale bark/root extract · Sassafras officinale root oil · 5-(Prop-2-en-1-yl)-2H-1,3-benzodioxole · 5-prop-2-enyl-1,3-benzodioxole · M-allyl pyrocatechinmethylene ether · Rhyuno oil · Shikomol · 1,2-Methylenedioxy-4-allylbenzene · 1,3-Benzodioxole, 5-(2-propenyl)- · 1,3-benzodioxole, 5-(2- propen-1-yl)- · 1-Allyl-3,4-methylenedioxybenzene · 3, 4-Methylenedioxy-1-allylbenzene · 3,4-Methylenedioxy-allylbenzene · 3-(3,4-Methylenedioxyphenyl)prop-1-ene · 4-ALLYL-1,2-METHYLENEDIOXYBENZENE · 4-Allyl-1,2-(methylenedioxy)benzene · 4-Allylpyrocatechol formaldehyde acetal · 5-(2-Propenyl)-1,3-benzodioxole · 5-allyl-1,3-benzodioxole · Allylcatechol methylene ether · Allyldioxybenzene methylene ether · Allylpyrocatechol methylene ether · Benzene, 4-ALLYL-1,2-(METHYLENEDIOXY)- · Safrole--prohibited · Safrene · Safrol · Safrole MF · Shikimol · Shikimole · allyl-1,3-benzodioxole (from natural food source) · m-Allylpyrocatechin methylene ether

What it does

Used in consumer products as a fragrance ingredient and a flavouring.

• Fragrance
• Flavouring

Is it a concern?

Critical concern: classified for carcinogenic, mutagenic or reproductive toxicity (CMR). It is banned in EU cosmetics.

Why it's flagged

• Cmr

Safrole, except for normal content in the natural essences used and provided that the concentration does not exceed: 100 ppm in the finished cosmetic product, 50 ppm in products for dental and oral hygiene, and provided that Safrole is not present in toothpastes intended specifically for children is prohibited in cosmetic products under Annex II of the EU Cosmetics Regulation (EC) 1223/2009.

RestrictedEU EC — banned

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

• EU Annex II — prohibited
• EU prohibited in cosmetics

• EU·EC

  Annex II of EU Cosmetics Regulation (EC) 1223/2009: substances prohibited in cosmetic products. CMR: Carcinogenic Cat. 1B(),Mutagenic Cat. 2()

  banned
  View source →

• EU·CosIng·ActiveCosmetics Regulation annex II / ref 360.

  • Cosmetics Regulation annex II / ref 360.Source →
• US·EPA·commercial use observedEPA CPDat observed this chemical in 8 composition records across product categories including Laboratory supplies, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.

  • EPA CPDat observed this chemical in 8 composition records across product categories including Laboratory supplies, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.Source →
• US·FDA·listed in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.

  • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Safrole. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

• SCCS

  EU Scientific Committee on Consumer Safety

  No SCCS opinion on file.

• CIR

  Cosmetic Ingredient Review (US expert panel)

  No CIR safety assessment on file.