Used in cosmetics as a fragrance ingredient.

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
cleaning
industrial
pharma

Indole

CAS 82451-55-6

Also registered as 1 other CAS number

120-72-9

Concern score

Not assessed — no hazard data yet.

Indole in plain language

What it is: Also known as Indol · 1H-Indole · 2,3-BENZOPYRROLE · 1-Azaindene · 1-Benzazole · 1H- Indole
Show all 12 names
2,3-Benzopyrole · Benzopyrrole · Caswell No. 498B · Indole, 3-Benzopyrrole, 1-benzazole · Ketole · Indolum
What it does: Used in cosmetics as a fragrance ingredient.
Perfuming
Fragrance
Flavouring
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Indole appears in these published regulatory listings.

In marketed US drugs

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Industrial

EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 21 composition records across product categories including Laboratory supplies, Cleaning products and household care, Personal care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.
- EPA CPDat observed this chemical in 21 composition records across product categories including Laboratory supplies, Cleaning products and household care, Personal care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 11 active drug products and 13 total products.
- FDA NDC lists this ingredient in 11 active drug products and 13 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Indole. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Indole yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated November 2017
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2029-10-17
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Indole in a product composition. These are source records, not Greenveil catalog products.

Source records

Named organisations

Laboratory suppliesCleaning products and household carePersonal careVehicle

Typical roles

PerfumingFragranceFlavouring

See products using Indole →