Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- cleaning
- food
- industrial
Polysorbate 80
CAS 1286269-72-4
Anti-static agent · Cleaning agent · Dispersing agent
Concern score
Not assessed — no hazard data yet.
Why it's flagged
EPA CPDat observed this chemical in 1566 composition records across product categories including Food and drug, Pesticides, Raw materials.
Regulation
No restrictions found. Polysorbate 80 appears in these published regulatory listings.
- commercial_presence
- consumer_product_presence
- cpdat_category:beauty|cleaning|pharma|food|industrial
- currently_marketed_ndc
- definition_level:incomplete
- definition_type:primary
- inactive_ingredient_database
- ingredient_type:ingredient substance
USFDAinactive ingredient database79 entries — 17 administration routes
- Route: AURICULAR (OTIC); Dosage form: DROPS; Potency: 0.02 %w/wSource →
- Route: AURICULAR (OTIC); Dosage form: SOLUTION; Potency: 0.2 %w/wSource →
- Route: AURICULAR (OTIC); Dosage form: SOLUTION/ DROPS; Maximum daily exposure: 13 mgSource →
- Route: AURICULAR (OTIC); Dosage form: SUSPENSION; Potency: 1 %w/vSource →
- Route: INTRA-ARTICULAR; Dosage form: INJECTION; Maximum daily exposure: 4 mgSource →
- Route: INTRA-ARTICULAR; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 5 mgSource →
- Route: INTRA-ARTICULAR; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 4 mgSource →
- Route: INTRALESIONAL; Dosage form: INJECTION; Maximum daily exposure: 4 mgSource →
- Route: INTRALESIONAL; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 4 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION; Potency: 4 %w/vSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 4 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 1 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, SOLUTION; Potency: 5 %w/vSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 4 mgSource →
- Route: INTRASYNOVIAL; Dosage form: INJECTION; Potency: 0.2 %w/vSource →
- Route: INTRASYNOVIAL; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 4 mgSource →
- Route: INTRAVENOUS; Dosage form: CONCENTRATE; Maximum daily exposure: 4680 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 4680 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 53 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 900 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 1170 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION, CONCENTRATE; Maximum daily exposure: 4739 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, SUSPENSION; Potency: 0.5 %w/vSource →
- Route: INTRAVENOUS; Dosage form: LIQUID; Maximum daily exposure: 720 mgSource →
- Route: INTRAVENOUS; Dosage form: SOLUTION; Maximum daily exposure: 900 mgSource →
- Route: INTRAVITREAL; Dosage form: INJECTION, SUSPENSION; Potency: 0.02 %w/vSource →
- Route: NASAL; Dosage form: SPRAY; Potency: 0.01 mgSource →
- Route: NASAL; Dosage form: SPRAY, METERED; Potency: 0.1 mg/1mlSource →
- Route: OPHTHALMIC; Dosage form: DROPS; Potency: 0.05 %w/wSource →
- Route: OPHTHALMIC; Dosage form: EMULSION; Maximum daily exposure: 26 mgSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION; Maximum daily exposure: 8 mgSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION, GEL FORMING, EXTENDED RELEASE; Potency: 0.05 %w/wSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: 0.25 %w/vSource →
- Route: OPHTHALMIC; Dosage form: SUSPENSION; Maximum daily exposure: 1 mgSource →
- Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Maximum daily exposure: 1 mgSource →
- Route: ORAL; Dosage form: CAPSULE; Potency: 418.37 mgSource →
- Route: ORAL; Dosage form: CAPSULE, COATED; Potency: 0.04 mgSource →
- Route: ORAL; Dosage form: CAPSULE, COATED PELLETS; Potency: 2 mgSource →
- Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Maximum daily exposure: 23 mgSource →
- Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Maximum daily exposure: 10 mgSource →
- + 39 more entries not shown
USEPAcommercial use observedEPA CPDat observed this chemical in 1566 composition records across product categories including Food and drug, Pesticides, Raw materials. EPA CPDat classifies this chemical for functional uses including Emulsifier, Fragrance, Surfactant (surface active agent).
- EPA CPDat observed this chemical in 1566 composition records across product categories including Food and drug, Pesticides, Raw materials. EPA CPDat classifies this chemical for functional uses including Emulsifier, Fragrance, Surfactant (surface active agent).Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 14 active drug products and 14 total products.
- FDA NDC lists this ingredient in 14 active drug products and 14 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as polymer.
- openFDA substance registry classifies this ingredient as polymer.Source →
Evidence
No graded sources yet for Polysorbate 80. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
Where it appears
Prevalence of Polysorbate 80 in our catalog (epa_cpdat).
Products
1,566
Brands
6
Food and drugPesticidesRaw materialsCleaning and safetyIndustrial productsPersonal care
Typical roles
Anti-static agentCleaning agentDispersing agentEmulsifierFlavouring and nutrientFragranceLubricating agentPharmaceutical
Found in these products
- Effaclar duo+La Roche-Posay · 3337875863377Critical
- Dermo ProtectDeliplus · CosmeticsCritical
- BIODERMA Sébium Hydra 40 ml eBioderma · Non Food ProductsCritical
- oral b completeOral BCritical
- DOVE Crème Hydratante Corps Soie Pot 300mlunilever, dove · BodyMinor
- Extra Frisch Cleanblend-a-med · ToothpastesCritical
- Effaclar Duo (+) Unifiant Teinte LightLa Roche-PosayCritical
- Gel de argánDeliplus · Non AlimentaireHigh
- Cicaplast Baume B5 SPF50La Roche-PosayCritical
- Oral-B 3D White Arctic Fresh TandpastaOralB · MondverzorgingHigh
- AZ 3D White Ultra White dentifricioOral-B · DentifricioCritical
- Complete: Freschezza DelicataAZ · DentifricioCritical
- HismileTeeth Brightening V34 Colour Corrector SerumHiSmile, Angel Consulting · MondverzorgingLow
- Tea Tree Oil Mouthwash SpearmintDesert Essence · Non Food ProductsHigh
- styl ista curlsL'Oréal · BeauteMinor
- ORAL-B JUNIORNon Food ProductsCritical
- Retinol Night CreamTiger Moon · FaceHigh
- Soft Mint mouth washFlux · HygieneCritical
- Miracle ScrubRituals · Hand ScrubCritical
- Yeauty Paradise Punch Eye Pad MaskBeautyCritical
- Mountain Breeze Spearmint Pocket PacksMountain Breeze · Mouth FreshenerHigh
- Arctic Berry Mouth RinseDesert Essence · HygieneCritical
- Mint 15 Energy Pouches (100 MG)WIP
- Blend a med RundumschutzHygieneCritical
