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  • cleaning

4-Pentanolide

CAS 219630-19-0

Also registered as 2 other CAS numbers

57129-69-8 · 108-29-2

4-Pentanolide chemical structure

Concern score

Not assessed — no hazard data yet.

4-Pentanolide in plain language

What it is

On cosmetic ingredient lists it appears as “Gamma-valerolactone”.

Also known as Gamma-valerolactone · .gamma.-valerolactone · (rs)-.gamma.-pentalactone · (±)-.gamma.-methylbutyrolactone · .gamma.-methyl-.gamma.-butyrolactone · 4-HYDROXYPENTANOIC acid .gamma.-lactone

Show all 30 names

5-Methyloxolan-2-one · Pentanoic acid, 4-HYDROXY-, .gamma.-lactone · Valeric acid, 4-HYDROXY-, .gamma.-lactone · (+/-)-.gamma.-methylbutyrolactone · (.+-.)-4-Methylbutyrolactone · (.+-.)-γ-Methylbutyrolactone · (.+-.)-γ-Pentalactone · (.+-.)-γ-Valerolactone · (RS)-γ-Pentalactone · 2(3H)-Furanone, dihydro-5-methyl- · 3-Methyl-n-γ-butyrolactone · 4-Hydroxypentanoic acid lactone · 4-Hydroxyvaleric acid lactone · 4-Methyl-4-hydroxybutanoic acid lactone · 4-Methyl-gamma-butyrolactone · 4-Valerolactone · 5-METHYLDIHYDRO-2(3H)-FURANONE · 5-Methyltetrahydro-2-furanone · DIHYDRO-5-METHYL-2(3H)-FURANONE · Dihydro-5-methyl-2(3H)-furanone; gamma-Valerolactone · Dihydro-5-methylfuran-2(3H)-one · Pentano-1,4-lactone · gamma-Pentalactone · γ-Valerolactone

What it does

Used in cosmetics as a fragrance ingredient.

  • Perfuming
  • Fragrance
  • Flavouring
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. 4-Pentanolide appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Cleaning
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 4 composition records across product categories including Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 4 composition records across product categories including Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for 4-Pentanolide. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for 4-Pentanolide yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated February 8, 2019

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed 4-Pentanolide in a product composition. These are source records, not Greenveil catalog products.

Source records

4

Named organisations

5

Cleaning products and household care

Typical roles

PerfumingFragranceFlavouring
See products using 4-Pentanolide →