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Simethicone

CAS 1646-73-7 · 40/100 · High conf.

Also registered as 3 other CAS numbers

9006-05-7 · 39349-90-1 · 8050-81-5

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Simethicone in plain language

What it is

Also known as Polydimethylsiloxane · Aligest Plus · Antifoam A · Barcroft SIM-DC 100 · DC Antifoam A · Mylicon

Show all 9 names

Silfoam SE 2 · dimethyl polysiloxane · simeticone

What it does

Used in cosmetics as an emollient, a skin-conditioning agent and a hair conditioner. Silica, hydrated, compounds with poly(dimethylsiloxane).

  • Emollient
  • Skin conditioning
  • Hair conditioning
  • Antifoaming
  • Anticaking agent, antifoaming agent
  • Conditioner
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 886 composition records across product categories including Food and drug, Personal care, Cleaning products and household care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Simethicone appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • EUCosIngActiveSilica, hydrated, compounds with poly(dimethylsiloxane)
    • Silica, hydrated, compounds with poly(dimethylsiloxane)Source →
  • GLOBALJECFA0-1.5 mg/kg bwJECFA evaluation lists ADI 0-1.5 mg/kg bw. Functional class: anticaking agent, antifoaming agent.
    • JECFA evaluation lists ADI 0-1.5 mg/kg bw. Functional class: anticaking agent, antifoaming agent.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 886 composition records across product categories including Food and drug, Personal care, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Defoamer, Softener and conditioner, Silicone.
    • EPA CPDat observed this chemical in 886 composition records across product categories including Food and drug, Personal care, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Defoamer, Softener and conditioner, Silicone.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI 0-1.5 mg/kg bw. Functional class: anticaking agent, antifoaming agent.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Simethicone yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated September 2018

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Simethicone in a product composition. These are source records, not Greenveil catalog products.

Source records

886

Named organisations

6

Food and drugPersonal careCleaning products and household careConstructionRaw materials

Typical roles

EmollientSkin conditioningHair conditioningAntifoamingAnticaking agent, antifoaming agentConditioner
See products using Simethicone →

Catalog

Found in these products

Their ingredient lists include Simethicone; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 88 →Find products without it →