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Creatine monohydrate

CAS 6020-87-7 · 20/100 · High conf.

Creatine monohydrate chemical structure

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Creatine monohydrate in plain language

What it is

Also known as Creatine · N-Carbamimidoyl-N-methylglycine--water (1/1) · Monohydrate creatine · 2-(1-Methylguanidino)acetic acid hydrate · Creapure · Creatine Supplement

Show all 15 names

Creatine hydrate · Creatine monohydrate, >=98% · Glycine, n-(aminoiminomethyl)-n-methyl-, monohydrate · Glycine, N-(aminoiminomethyl)-N-methyl-, hydrate · Glycine, N-(aminoiminomethyl)-N-methyl-, hydrate (1:1) · N-(Aminoiminomethyl)-N-methylglycine monohydrate · N-(aminoiminomethyl)-N-methyl-Glycine, monohydrate · N-Guanyl-N-methylglycine · UNII-9603LN7R2Q

What it does

We don't have a plain-language description for Creatine monohydrate yet.

Is it a concern?
Minor concern: no hazard classifications on record.

Why it's flagged

EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Creatine monohydrate appears in these published regulatory listings.

  • In marketed US drugs
  • USFDAmarketed drug occurrence2 entries
    • FDA NDC lists this ingredient in 3 active drug products and 5 total products.Source →
    • FDA NDC lists this ingredient in 1 active drug products and 1 total products.Source →
  • EUEFSAEFSA opinionOpinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to creatine monohydrate for use in foods for particular nutritional uses (EFSA AFC)
    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to creatine monohydrate for use in foods for particular nutritional uses (EFSA AFC)Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    No JECFA evaluation on file.

  • EFSA

    European Food Safety Authority

    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request from the Commission related to creatine monohydrate for use in foods for particular nutritional uses (EFSA AFC)

      2004 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Creatine monohydrate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2029-10-17

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Creatine monohydrate in a product composition. These are source records, not Greenveil catalog products.

Source records

5

See products using Creatine monohydrate →

Catalog

Found in these products

Their ingredient lists include Creatine monohydrate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 380 →Find products without it →