Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
EPA CPDat observed this chemical in 98 composition records across product categories including Food and drug, Laboratory supplies, Raw materials.
Concern score
The concern value reflects this ingredient's chemical identity — its hazard profile from the published classifications and regulatory status below — not the safety of a product it appears in. A score near 40 is the baseline for ingredients with no specific signal (water scores 40 by design), so a mid-range value is not a safety verdict.
Concern score 5/100 (low) · high confidence.
Prevalence of MANNITOL in our catalog (epa_cpdat).
Products
98
Brands
5
Typical roles
Catalog
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.
Source: chemindex_name_match
Primary documents currently linked to this ingredient record.
Structured claim signals pulled from linked ingredient research.
Published jurisdiction-level classifications and regulatory designations for this ingredient.
US
EPA
EPA CPDat observed this chemical in 98 composition records across product categories including Food and drug, Laboratory supplies, Raw materials. EPA CPDat classifies this chemical for functional uses including Humectant, Deodorizer, Softener and conditioner.
US
FDA
Route: BUCCAL; Dosage form: GUM, CHEWING; Maximum daily exposure: 891 mg
US
FDA
Bioderma
Bioderma
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
The published evidence profile currently shaping this ingredient record.
Route: BUCCAL; Dosage form: TABLET; Maximum daily exposure: 360 mg
US
FDA
Route: INTRAMUSCULAR; Dosage form: INJECTION; Potency: 106.6 mg
US
FDA
Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 300 mg
US
FDA
Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 164 mg
US
FDA
Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 113 mg
US
FDA
Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 71 mg
US
FDA
Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 105 mg
US
FDA
Route: INTRAMUSCULAR; Dosage form: POWDER, FOR SUSPENSION; Potency: 6.75 %w/v
US
FDA
Route: INTRAVENOUS; Dosage form: CONCENTRATE; Maximum daily exposure: 220 mg
US
FDA
Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 15200 mg
US
FDA
Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 980.4 mg
US
FDA
Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 181 mg
US
FDA
Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 15400 mg
US
FDA
Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 15400 mg
US
FDA
Route: INTRAVENOUS; Dosage form: INJECTION, SUSPENSION; Potency: 2.5 %w/v
US
FDA
Route: INTRAVENOUS; Dosage form: SOLUTION; Maximum daily exposure: 15400 mg
US
FDA
Route: INTRAVENOUS; Dosage form: SOLUTION, CONCENTRATE; Maximum daily exposure: 220 mg
US
FDA
Route: NASAL; Dosage form: POWDER; Maximum daily exposure: 13 mg
US
FDA
Route: OPHTHALMIC; Dosage form: GEL; Maximum daily exposure: 25 mg
US
FDA
Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 4.7 %w/v
US
FDA
Route: OPHTHALMIC; Dosage form: SOLUTION, GEL FORMING / DROPS; Maximum daily exposure: 4 mg
US
FDA
Route: OPHTHALMIC; Dosage form: SOLUTION, GEL FORMING, EXTENDED RELEASE; Potency: 4.35 %w/w
US
FDA
Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: 4.6 %w/v
US
FDA
Route: OPHTHALMIC; Dosage form: SUSPENSION; Maximum daily exposure: 6 mg
US
FDA
Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Potency: 3.3 %w/v
US
FDA
Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 1562 mg
US
FDA
Route: ORAL; Dosage form: CAPSULE, COATED PELLETS; Maximum daily exposure: 14 mg
US
FDA
Route: ORAL; Dosage form: CAPSULE, COATED, EXTENDED RELEASE; Potency: NA
US
FDA
Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Maximum daily exposure: 2043 mg
US
FDA
Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Maximum daily exposure: 160 mg
US
FDA
Route: ORAL; Dosage form: GRANULE; Maximum daily exposure: 1328 mg
US
FDA
Route: ORAL; Dosage form: GRANULE, FOR SUSPENSION; Maximum daily exposure: 6000 mg
US
FDA
Route: ORAL; Dosage form: LOZENGE; Maximum daily exposure: 20546 mg
US
FDA
Route: ORAL; Dosage form: POWDER; Maximum daily exposure: 4352 mg
US
FDA
Route: ORAL; Dosage form: POWDER, FOR SOLUTION; Maximum daily exposure: 3767 mg
US
FDA
Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 7093 mg
US
FDA
Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 869 mg
US
FDA
Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: 2464.6 mg
US
FDA
Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 3391 mg
US
FDA
Route: ORAL; Dosage form: TABLET, CHEWABLE; Maximum daily exposure: 3726 mg
US
FDA
Route: ORAL; Dosage form: TABLET, CHEWABLE, EXTENDED RELEASE; Maximum daily exposure: 616 mg
US
FDA
Route: ORAL; Dosage form: TABLET, COATED; Potency: 177.7 mg
US
FDA
Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 639 mg
US
FDA
Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 1086 mg
US
FDA
Route: ORAL; Dosage form: TABLET, FILM COATED; Maximum daily exposure: 2309 mg
US
FDA
Route: ORAL; Dosage form: TABLET, FILM COATED, EXTENDED RELEASE; Maximum daily exposure: 543 mg
US
FDA
Route: ORAL; Dosage form: TABLET, FOR SUSPENSION; Maximum daily exposure: 7621 mg
US
FDA
Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Maximum daily exposure: 4364 mg
US
FDA
Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING, DELAYED RELEASE; Maximum daily exposure: 1568 mg
US
FDA
Route: ORAL; Dosage form: TROCHE; Maximum daily exposure: 14594 mg
US
FDA
Route: PARENTERAL; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 200 mg
US
FDA
Route: RESPIRATORY (INHALATION); Dosage form: POWDER; Maximum daily exposure: 6 mg
US
FDA
Route: SUBCUTANEOUS; Dosage form: INJECTION; Maximum daily exposure: 675 mg
US
FDA
Route: SUBCUTANEOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 35 mg
US
FDA
Route: SUBCUTANEOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 180 mg
US
FDA
Route: SUBCUTANEOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 658 mg
US
FDA
Route: SUBCUTANEOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 99 mg
US
FDA
Route: SUBCUTANEOUS; Dosage form: SOLUTION; Potency: 1.59 %w/v
US
FDA
Route: SUBLINGUAL; Dosage form: TABLET; Maximum daily exposure: 495 mg
US
FDA
Route: SUBLINGUAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Potency: 10.25 mg
US
FDA
Route: SUBMUCOSAL; Dosage form: INJECTION, SOLUTION; Potency: 2.94 %w/v
US
FDA
Route: TOPICAL; Dosage form: SOLUTION; Potency: 4 %w/v
US
FDA
Route: TOPICAL; Dosage form: SUSPENSION/ DROPS; Potency: 0.3 %w/v
US
FDA
FDA NDC lists this ingredient in 12 active drug products and 12 total products.
US
FDA
openFDA substance registry classifies this ingredient as concept.
US
FDA
openFDA substance registry classifies this ingredient as chemical.