# MANNITOL URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid1023235 Categories: beauty, cleaning, food, industrial, pharma Functions: Anti-caking agent, Binder, Deodorizer, Flavouring and nutrient, Fragrance, Humectant, Lubricating agent, Processing aids not otherwise specified, Softener and conditioner, Solvent Identifier: DTXSID1023235 > MANNITOL is used as anti-caking agent / binder. EPA CPDat observed this chemical in 98 composition records across product categories including Food and drug, Laboratory supplies, Raw materials. Assessed from 78 sources. ## Safety assessment - Chemical concern: not yet assessed - Rationale: EPA CPDat observed this chemical in 98 composition records across product categories including Food and drug, Laboratory supplies, Raw materials. ## Regulatory status - US: commercial use observed — EPA CPDat observed this chemical in 98 composition records across product categories including Food and drug, Laboratory supplies, Raw materials. EPA CPDat classifies this chemical for functional uses including Humectant, Deodorizer, Softener and conditioner. - US: inactive ingredient database — Route: BUCCAL; Dosage form: GUM, CHEWING; Maximum daily exposure: 891 mg - US: inactive ingredient database — Route: BUCCAL; Dosage form: TABLET; Maximum daily exposure: 360 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION; Potency: 106.6 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 300 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 164 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 113 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION; Maximum daily exposure: 71 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 105 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: POWDER, FOR SUSPENSION; Potency: 6.75 %w/v - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: CONCENTRATE; Maximum daily exposure: 220 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 15200 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 980.4 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 181 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 15400 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 15400 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, SUSPENSION; Potency: 2.5 %w/v - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: SOLUTION; Maximum daily exposure: 15400 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: SOLUTION, CONCENTRATE; Maximum daily exposure: 220 mg - US: inactive ingredient database — Route: NASAL; Dosage form: POWDER; Maximum daily exposure: 13 mg - US: inactive ingredient database — Route: NASAL; Dosage form: SPRAY; Potency: 41.5 mg - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: GEL; Maximum daily exposure: 25 mg - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 4.7 %w/v - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION, GEL FORMING / DROPS; Maximum daily exposure: 4 mg - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION, GEL FORMING, EXTENDED RELEASE; Potency: 4.35 %w/w - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: 4.6 %w/v - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SUSPENSION; Maximum daily exposure: 6 mg - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Potency: 3.3 %w/v - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 1562 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, COATED PELLETS; Maximum daily exposure: 14 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, COATED, EXTENDED RELEASE; Potency: NA - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Maximum daily exposure: 2043 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Maximum daily exposure: 160 mg - US: inactive ingredient database — Route: ORAL; Dosage form: GRANULE; Maximum daily exposure: 1328 mg - US: inactive ingredient database — Route: ORAL; Dosage form: GRANULE, FOR SUSPENSION; Maximum daily exposure: 6000 mg - US: inactive ingredient database — Route: ORAL; Dosage form: LOZENGE; Maximum daily exposure: 20546 mg - US: inactive ingredient database — Route: ORAL; Dosage form: POWDER; Maximum daily exposure: 4352 mg - US: inactive ingredient database — Route: ORAL; Dosage form: POWDER, FOR SOLUTION; Maximum daily exposure: 3767 mg - US: inactive ingredient database — Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 7093 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 869 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Potency: 2464.6 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 3391 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, CHEWABLE; Maximum daily exposure: 3726 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, CHEWABLE, EXTENDED RELEASE; Maximum daily exposure: 616 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, COATED; Potency: 177.7 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 639 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 1086 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, FILM COATED; Maximum daily exposure: 2309 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, FILM COATED, EXTENDED RELEASE; Maximum daily exposure: 543 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, FOR SUSPENSION; Maximum daily exposure: 7621 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Maximum daily exposure: 4364 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING, DELAYED RELEASE; Maximum daily exposure: 1568 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TROCHE; Maximum daily exposure: 14594 mg - US: inactive ingredient database — Route: ORAL; Dosage form: WAFER; Potency: 642 mg - US: inactive ingredient database — Route: PARENTERAL; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 200 mg - US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: POWDER; Maximum daily exposure: 6 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION; Maximum daily exposure: 675 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Potency: 35 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Maximum daily exposure: 180 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 658 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 99 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: SOLUTION; Potency: 1.59 %w/v - US: inactive ingredient database — Route: SUBLINGUAL; Dosage form: TABLET; Maximum daily exposure: 495 mg - US: inactive ingredient database — Route: SUBLINGUAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Potency: 10.25 mg - US: inactive ingredient database — Route: SUBMUCOSAL; Dosage form: INJECTION, SOLUTION; Potency: 2.94 %w/v - US: inactive ingredient database — Route: TOPICAL; Dosage form: SOLUTION; Potency: 4 %w/v - US: inactive ingredient database — Route: TOPICAL; Dosage form: SUSPENSION/ DROPS; Potency: 0.3 %w/v - US: marketed drug occurrence — FDA NDC lists this ingredient in 12 active drug products and 12 total products. - US: listed in openFDA substance — openFDA substance registry classifies this ingredient as concept. - US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical. _Assessed by Greenveil._