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Propoxyphene

CAS 469-62-5

Also registered as 4 other CAS numbers

77-50-9 · 2621-61-6 · 3818-94-8 · 21086-94-2

Propoxyphene chemical structure

Concern score

Not assessed — no hazard data yet.

Propoxyphene in plain language

What it is

Also known as Dextropropoxyphene · (+)-propoxyphene · Algafan · D-propoxyphene · Depromic · Dextropropoxyphen

Show all 20 names

Propoxyphene, (+)- · Propoxyphene, d- · (+)-1,2-Diphenyl-2-propionoxy-3-methyl-4-dimethylaminobutane · 4-Dimethylamino-3-methyl-1,2-diphenyl-2-propoxybutane · Antalvic · Destropropossifene · Dextropropoxifeno · Dextropropoxyphene (INN) · Dextropropoxyphenum · Dextroproxifeno · IDS-ND-004(SECT.2) · J5.928E · Proxyvon · SK-65

What it does

We don't have a plain-language description for Propoxyphene yet.

Recorded functional uses: Pharmaceutical

Is it a concern?
We haven't assessed a concern score for this ingredient yet.

Regulation

No restrictions found. Propoxyphene appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Pharmaceutical.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Evidence & sources

No graded research studies for Propoxyphene yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

  • EPA Chemical and Products Database

    exposure · updated November 2007

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (2)
Openfda substance

nikkajiweb.jst.go.jp

Openfda substance

jpet.aspetjournals.org

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Propoxyphene in a product composition. These are source records, not Greenveil catalog products.

Named organisations

5

Typical roles

Pharmaceutical
See products using Propoxyphene →