beauty
cleaning
industrial

Octylisothiazolinone

CAS 12673-72-2

Also registered as 7 other CAS numbers

53028-82-3 · 122667-23-6 · 245125-70-6 · 249757-59-3 · 1135442-68-0 · 1617530-25-2 · 26530-20-1

Concern score

Not assessed — no hazard data yet.

Octylisothiazolinone in plain language

What it is: Also known as Octhilinone · 2-n-Octyl-4-isothiazolin-3-one · 2-Octyl-1,2-thiazol-3(2H)-one · 2-octyl-1,2-thiazol-3-one · 3(2H)-ISOTHIAZOLONE, 2-OCTYL · 2-OCTYL-3(2H)-ISOTHIAZOLONE
Show all 36 names
2-Octyl-2H-isothiazol-3-on · 2-Octyl-2H-isothiazol-3-one · 2-Octyl-3(2H)-isothiazolinone · 2-Octyl-3-isothiazolinone · 2-Octyl-3-isothiazolone · 2-n-Octyl-3-isothiazolone · 2-n-Octyl-4-isothiozolin-3-one · 2-n-Octylisothiazolin-3-one · 2-n-octyl-4-isothiazolin-3-one (mfr cas # 26530-30-1) · 2-octil-2H-isotiazol-3-ona · 2-octyl-4-isothiazolin-3-one · 3(2H)-Isothiazolone, 2-octyl- · 4-Isothiazolin-3-one, 2-octyl- · Isothiazolinone derivative · Kathon · Koralone 500 preservative · Kathon 4200 · Kathon LM · Kathon LP preservative · Kathon SP 70 · Micro-chek 11 · Micro-chek 11D · Micro-chek skane · Microbicide M-8 · Pancil · Pancil-T · Rh 893 · Skane 8 · antimicrobial preservative · paint preservatives
What it does: Used in cosmetics as an antimicrobial.
Antimicrobial
Antioxidant
Preservative
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Octylisothiazolinone appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Beauty
Cleaning
Industrial

EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 293 composition records across product categories including Home maintenance, Construction and building materials, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Preservative, Biocide, Antioxidant.
- EPA CPDat observed this chemical in 293 composition records across product categories including Home maintenance, Construction and building materials, Cleaning and safety. EPA CPDat classifies this chemical for functional uses including Preservative, Biocide, Antioxidant.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Octylisothiazolinone. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Octylisothiazolinone yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated november 7, 2016
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Octylisothiazolinone in a product composition. These are source records, not Greenveil catalog products.

Source records

293

Named organisations

Home maintenanceConstruction and building materialsCleaning and safetyCleaning products and household careRaw materialsVehicle

Typical roles

AntimicrobialAntioxidantPreservative

See products using Octylisothiazolinone →

Catalog

Found in these products

Their ingredient lists include Octylisothiazolinone; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 51 →Find products without it →