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Methylcellulose (15 mpa.s)

CAS 39384-65-1 · 40/100 · High conf.

Also registered as 6 other CAS numbers

53568-34-6 · 71812-19-6 · 88402-84-0 · 99638-59-2 · 730985-58-7 · 9004-67-5

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Methylcellulose (15 mpa.s) in plain language

What it is

On cosmetic ingredient lists it appears as “Methylcellulose”.

Also known as Methylcellulose · Methylcellulose (1500 mpa.s) · Methylcellulose (400 mpa.s) · Methyl cellulose · Methylcellulose (100 mpa.s) · Methylcellulose (25 mpa.s)

Show all 36 names

Methylcellulose (100 cps) · Methylcellulose (15 cps) · Methylcellulose (1500 cps) · Methylcellulose (25 cps) · Methylcellulose (400 cps) · Benecel mc A15C · Methocel a 25 · Methylcellulose 1500 · Methylcellulose 400 · Methylcellulose SM-25 (25 cps) · Anyaddy MC 40H · Benecel mc A15 · Benecel 143HR · Benecel A 15 · Benecel A 40M · Benecel M 011 · Benecel M 021 · Culminal MC 7000PF · Methocel A15 lv · Methocel A15 premium · Methocel A25 · Methocel A4C · Methocel A4CPCG · Metolose sm 100 · Metolose sm 15 · Metolose sm 1500 · Metolose sm 25 · Metolose sm 400 · methyl ether cellulose. · methylcellulosum

What it does

Used in cosmetics as a binder, an emulsion stabiliser and a light stabiliser.

  • Binding
  • Emulsion stabilising
  • Light stabilizer
  • Viscosity controlling
  • Thickener, emulsifier, stabilizer
  • Emulsifier
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 244 composition records across product categories including Batteries, Laboratory supplies, Home maintenance.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Methylcellulose (15 mpa.s) appears in these published regulatory listings.

  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • Industrial
  • USFDAinactive ingredient database10 entries
    • Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 360 mgSource →
    • Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 5 mgSource →
    • Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 384 mgSource →
    • Route: ORAL; Dosage form: TABLET, FILM COATED; Maximum daily exposure: 68 mgSource →
    • Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 319 mgSource →
    • Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 3 mgSource →
    • Route: ORAL; Dosage form: TABLET; Potency: 33 mgSource →
    • Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Maximum daily exposure: 93 mgSource →
    • Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 17 mgSource →
    • Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 4 mgSource →
  • EUEFSAEFSA opinion2 entries
    • Safety and efficacy of methyl cellulose for all animal species (EFSA FEEDAP)Source →
    • Re-evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives (EFSA ANS)Source →
  • EUCosIngActiveCellulose, methyl ether
  • GLOBALJECFANOT SPECIFIEDJECFA evaluation lists ADI NOT SPECIFIED. Functional class: thickener, emulsifier, stabilizer.
    • JECFA evaluation lists ADI NOT SPECIFIED. Functional class: thickener, emulsifier, stabilizer.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 244 composition records across product categories including Batteries, Laboratory supplies, Home maintenance. EPA CPDat classifies this chemical for functional uses including Surface modifier, Viscosity modifier, Stabilizing agent.
    • EPA CPDat observed this chemical in 244 composition records across product categories including Batteries, Laboratory supplies, Home maintenance. EPA CPDat classifies this chemical for functional uses including Surface modifier, Viscosity modifier, Stabilizing agent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as polymer.
    • openFDA substance registry classifies this ingredient as polymer.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Safety and efficacy of methyl cellulose for all animal species (EFSA FEEDAP)

      2020 · EU EFSA listing · Read the source →

    • Re-evaluation of celluloses E 460(i), E 460(ii), E 461, E 462, E 463, E 464, E 465, E 466, E 468 and E 469 as food additives (EFSA ANS)

      2018 · EU EFSA listing · Read the source →

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI NOT SPECIFIED. Functional class: thickener, emulsifier, stabilizer.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Methylcellulose (15 mpa.s) yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated january 21, 2017

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
Reference links (4)
Openfda substance

msdssearch.dow.com

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Methylcellulose (15 mpa.s) in a product composition. These are source records, not Greenveil catalog products.

Source records

244

Named organisations

6

BatteriesLaboratory suppliesHome maintenanceCleaning and safetyArts and crafts/office suppliesRaw materials

Typical roles

BindingEmulsion stabilisingLight stabilizerViscosity controllingThickener, emulsifier, stabilizerEmulsifier
See products using Methylcellulose (15 mpa.s) →

Catalog

Found in these products

Their ingredient lists include Methylcellulose (15 mpa.s); each product's own rating depends on its whole formula, so it is shown on the product page, not here.