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TRIS(2-CARBOXYETHYL)PHOSPHINE hydrochloride

CAS 51805-45-9

TRIS(2-CARBOXYETHYL)PHOSPHINE hydrochloride chemical structure

Concern score

Not assessed — no hazard data yet.

TRIS(2-CARBOXYETHYL)PHOSPHINE hydrochloride in plain language

What it is

On cosmetic ingredient lists it appears as “Tris (2-CARBOXYETHYL)PHOSPHINE hcl”.

Also known as Tris (2-CARBOXYETHYL)PHOSPHINE hcl · Tcep hydrochloride · Tris(2-carboxyethyl)phosphine hydrochloride (1:1) · 3,3',3''-Phosphinetriyltripropanoic acid hydrochloride · M02624 · Propanoic acid, 3,3',3''-phosphinidynetris-, hydrochloride

Show all 14 names

Propionic acid, 3,3',3''-phosphinidynetri-, hydrochloride · Tcep hcl · TCEP Hydrochloride (0.5M in water) · TCEP Hydrochloride? · TCEP-HCl · Tris(2-carboxyethyl)phosphine, HCl · Tris(carboxyethyl)phosphine hydrochloride · UNII-H49AAM893K

What it does

Used in cosmetics as an anti-sebum and a binder.

  • Anti-sebum
  • Binding
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

Regulation

No restrictions found. TRIS(2-CARBOXYETHYL)PHOSPHINE hydrochloride appears in these published regulatory listings.

  • EUCosIngActiveTris (2-Carboxyethyl)Phosphine HCl is the organic compound that conforms to the formula.
    • Tris (2-Carboxyethyl)Phosphine HCl is the organic compound that conforms to the formula.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for TRIS(2-CARBOXYETHYL)PHOSPHINE hydrochloride. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for TRIS(2-CARBOXYETHYL)PHOSPHINE hydrochloride yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.