Skip to content
  • beauty
  • cleaning
  • food
  • pharma

Sucralose

CAS 1450725-31-1

Also registered as 1 other CAS number

56038-13-2

Sucralose chemical structure

Concern score

Not assessed — no hazard data yet.

Sucralose in plain language

What it is

Also known as 1',4',6'-TRICHLORO-GALACTOSUCROSE · 4,1',6'-TRICHLOROGALACTOSUCROSE · Aspasvit · San sweet sa 8020 · Sansweet su 100 · Sucrazit

Show all 18 names

Tgs · Trichlorogalactosucrose · 1',4,6'-Trichlorogalactosucrose · 4,1',6'-Trichloro-4,1',6'-trideoxygalactosucrose · E-955 · Ins NO.955 · INS-955 · Predillon SU 600 · Splenda · Trichlorogalacto-sucrose · Trichlorosucrose · sucralose and/or sodium saccharin

What it does

Used in cosmetics as a skin-conditioning agent.

  • Skin conditioning
  • Fragrance
  • Flavouring
  • Conditioner
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Sucralose appears in these published regulatory listings.

  • In marketed US drugs
  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Pharma
  • Food
  • USFDAinactive ingredient database22 entries — 4 administration routes
    • Route: NASAL; Dosage form: SPRAY; Maximum daily exposure: 2 mgSource →
    • Route: NASAL; Dosage form: SPRAY, METERED; Maximum daily exposure: 2 mgSource →
    • Route: ORAL; Dosage form: FILM; Maximum daily exposure: 1 mgSource →
    • Route: ORAL; Dosage form: FILM, SOLUBLE; Maximum daily exposure: 33 mgSource →
    • Route: ORAL; Dosage form: GRANULE; Potency: 5.4 mgSource →
    • Route: ORAL; Dosage form: GRANULE, FOR SUSPENSION; Maximum daily exposure: 23 mgSource →
    • Route: ORAL; Dosage form: LOZENGE; Maximum daily exposure: 115 mgSource →
    • Route: ORAL; Dosage form: POWDER, FOR SOLUTION; Maximum daily exposure: 414 mgSource →
    • Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 400 mgSource →
    • Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 800 mgSource →
    • Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 383 mgSource →
    • Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 16 mgSource →
    • Route: ORAL; Dosage form: SYRUP; Maximum daily exposure: 80 mgSource →
    • Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 45 mgSource →
    • Route: ORAL; Dosage form: TABLET, CHEWABLE; Maximum daily exposure: 28 mgSource →
    • Route: ORAL; Dosage form: TABLET, EFFERVESCENT; Maximum daily exposure: 1080 mgSource →
    • Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 1 mgSource →
    • Route: ORAL; Dosage form: TABLET, FOR SUSPENSION; Maximum daily exposure: 65 mgSource →
    • Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Maximum daily exposure: 60 mgSource →
    • Route: ORAL; Dosage form: TROCHE; Maximum daily exposure: 60 mgSource →
    • Route: SUBLINGUAL; Dosage form: TABLET; Maximum daily exposure: 12 mgSource →
    • Route: BUCCAL; Dosage form: GUM, CHEWING; Maximum daily exposure: 70 mgSource →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 294 composition records across product categories including Personal care, Food and drug. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Flavouring and nutrient, Fragrance.
    • EPA CPDat observed this chemical in 294 composition records across product categories including Personal care, Food and drug. EPA CPDat classifies this chemical for functional uses including Softener and conditioner, Flavouring and nutrient, Fragrance.Source →
  • USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 2 active drug products and 2 total products.
    • FDA NDC lists this ingredient in 2 active drug products and 2 total products.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Sucralose. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Sucralose yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA Chemical and Products Database

    exposure · updated september 6, 2017

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

codexalimentarius.net

Allergen profile

Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.

  • SoyContains · Oral (ingested)

    Source: chemindex_name_match

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Sucralose in a product composition. These are source records, not Greenveil catalog products.

Source records

294

Named organisations

6

Personal careFood and drug

Typical roles

Skin conditioningFragranceFlavouringConditioner
See products using Sucralose →

Catalog

Found in these products

Cosmetic and personal-care products that list Sucralose are shown first. Their ingredient lists include Sucralose; each product's own rating depends on its whole formula, so it is shown on the product page, not here.