# TRISODIUM CITRATE DIHYDRATE URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid1049437 Categories: beauty, cleaning, food, industrial, pharma Functions: Chelating agent, Crystal growth modifiers (nucleating agents), Preservative, Processing aids not otherwise specified, Stabilizing agent, pH regulating agent Identifier: DTXSID1049437 > TRISODIUM CITRATE DIHYDRATE is used as chelating agent / crystal growth modifiers (nucleating agents). EPA CPDat observed this chemical in 261 composition records across product categories including Laboratory supplies, Food and drug, Cleaning products and household care. Assessed from 53 sources. ## Safety assessment - Chemical concern: not yet assessed - Rationale: EPA CPDat observed this chemical in 261 composition records across product categories including Laboratory supplies, Food and drug, Cleaning products and household care. ## Regulatory status - US: commercial use observed — EPA CPDat observed this chemical in 261 composition records across product categories including Laboratory supplies, Food and drug, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Chelating agent, pH regulating agent, Preservative. - US: inactive ingredient database — Route: INTRA-ARTICULAR; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 25 mg - US: inactive ingredient database — Route: INTRACARDIAC; Dosage form: INJECTION; Maximum daily exposure: 21 mg - US: inactive ingredient database — Route: INTRACAVERNOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: 0.03 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION; Maximum daily exposure: 3480 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 1188 mg - US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: SOLUTION; Potency: 0.03 %w/v - US: inactive ingredient database — Route: INTRAOCULAR; Dosage form: INJECTION, SOLUTION, CONCENTRATE; Potency: 5.48 mg/1ml - US: inactive ingredient database — Route: INTRAOCULAR; Dosage form: SOLUTION; Maximum daily exposure: 27 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 3480 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 800 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 1188 mg - US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: SOLUTION; Maximum daily exposure: 41 mg - US: inactive ingredient database — Route: INTRAVITREAL; Dosage form: INJECTION, SUSPENSION; Potency: 0.17 %w/v - US: inactive ingredient database — Route: IRRIGATION; Dosage form: INJECTION, SOLUTION, CONCENTRATE; Potency: 0.55 %w/v - US: inactive ingredient database — Route: NASAL; Dosage form: SPRAY; Maximum daily exposure: 9 mg - US: inactive ingredient database — Route: NASAL; Dosage form: SPRAY, METERED; Maximum daily exposure: 1 mg - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 0.45 %w/v - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Maximum daily exposure: 1 mg - US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Maximum daily exposure: 7 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 35 mg - US: inactive ingredient database — Route: ORAL; Dosage form: CONCENTRATE; Maximum daily exposure: 104 mg - US: inactive ingredient database — Route: ORAL; Dosage form: ELIXIR; Maximum daily exposure: 68 mg - US: inactive ingredient database — Route: ORAL; Dosage form: GRANULE, FOR SUSPENSION; Maximum daily exposure: 4950 mg - US: inactive ingredient database — Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 5010 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 1200 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 5013 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 9 mg - US: inactive ingredient database — Route: ORAL; Dosage form: SYRUP; Maximum daily exposure: 705 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 896 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, CHEWABLE; Maximum daily exposure: 14 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 640 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 300 mg - US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, FILM COATED, EXTENDED RELEASE; Maximum daily exposure: 200 mg - US: inactive ingredient database — Route: RECTAL; Dosage form: SOLUTION; Maximum daily exposure: 773 mg - US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: POWDER; Maximum daily exposure: 17 mg - US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: SOLUTION; Maximum daily exposure: 24 mg - US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: SUSPENSION; Maximum daily exposure: 2 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION; Maximum daily exposure: 75 mg - US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 28 mg - US: inactive ingredient database — Route: SUBLINGUAL; Dosage form: FILM; Maximum daily exposure: 7 mg - US: inactive ingredient database — Route: SUBLINGUAL; Dosage form: TABLET; Maximum daily exposure: 51 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: CLOTH; Maximum daily exposure: 2 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 2 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: GEL; Potency: 0.18 %w/w - US: inactive ingredient database — Route: TOPICAL; Dosage form: LOTION; Maximum daily exposure: 328 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: SHAMPOO; Maximum daily exposure: 186 mg - US: inactive ingredient database — Route: TOPICAL; Dosage form: SOLUTION; Maximum daily exposure: 186 mg - US: marketed drug occurrence — FDA NDC lists this ingredient in 45 active drug products and 45 total products. - US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical. _Assessed by Greenveil._