What does Calcium hypophosphite do?

Used in cosmetics as a skin-conditioning agent and an oral-care ingredient. Calcium Phosphinate is the organic salt.

Is Calcium hypophosphite safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
industrial
pharma

Calcium hypophosphite

CAS 6298-64-2

Also registered as 1 other CAS number

7789-79-9

Calcium hypophosphite chemical structure

Concern score

Not assessed — no hazard data yet.

Calcium hypophosphite in plain language

What it is: On cosmetic ingredient lists it appears as “Calcium phosphinate”.
Also known as Calcium phosphinate · Calcium bis(dioxidophosphanium) · Calcium dihydrogen hypophosphite · Calcium salt phosphinic acid · Phosphinic acid, calcium salt (2:1) · Phosphinolate, 1-oxo-, calcium salt (2:1)
Show all 7 names
Calcarea hypophosphorosa
What it does: Used in cosmetics as a skin-conditioning agent and an oral-care ingredient. Calcium Phosphinate is the organic salt.
Skin conditioning
Oral care
Antioxidant
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Calcium hypophosphite appears in these published regulatory listings.

In marketed US drugs

Recorded in these product areas

Found in consumer products
Industrial

EUCosIngActiveCalcium Phosphinate is the organic salt that conforms to the formula
- Calcium Phosphinate is the organic salt that conforms to the formulaSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Flame retardant, Antioxidant.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Flame retardant, Antioxidant.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 4 active drug products and 4 total products.
- FDA NDC lists this ingredient in 4 active drug products and 4 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Calcium hypophosphite. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Calcium hypophosphite yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated February 8, 2019
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2026-12-31
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often FDA National Drug Code directory has listed Calcium hypophosphite in a product composition. These are source records, not Greenveil catalog products.

Source records

Typical roles

Skin conditioningOral careAntioxidant

See products using Calcium hypophosphite →