Poloxamer 338

CAS 691397-13-4

Also registered as 2 other CAS numbers

106392-12-5 · 126925-06-2

Concern score

Not assessed — no hazard data yet.

Poloxamer 338 in plain language

What it is: Also known as Crl-8131 · Pluronic F108 · 2-methyloxirane;oxirane · Adekanol f 108 · Poly(ethylene oxide-co-propylene oxide), block · F-108
Show all 22 names
Hydrowet · Magcyl · Pluracare f 108 · Pluronic F-108 · Pluracol V · Pluronic F · Pluronic F-68 · Pluronic L · Pluronic L 122 · Pluronic L-81 · Pluronic L44 · Proksanol · Proxanol · Regulaid · Slovanik · Tergitol(tm)xh(nonionic)
What it does: We don't have a plain-language description for Poloxamer 338 yet.
Is it a concern?: We haven't assessed a concern score for this ingredient yet.

What we know about this ingredient

EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

Regulation

No restrictions found. Poloxamer 338 appears in these published regulatory listings.

USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as polymer.
- openFDA substance registry classifies this ingredient as polymer.Source →

Evidence & sources

No graded research studies for Poloxamer 338 yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

4 data sources

Where this comes from

EPA DSSTox Identifiers
chemistry · updated 2025-12-29
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FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Reference links (2)

Openfda substance

worldaccount.basf.com

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Openfda substance

sanrisechem.com

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Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Catalog

Found in these products

Their ingredient lists include Poloxamer 338; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 30 →Find products without it →