What does Acetaminophen do?

Used in cosmetics as a skin-conditioning agent.

Is Acetaminophen safe?

High concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

beauty
food
industrial
pharma

Acetaminophen

CAS 8055-08-1 · 60/100 · High conf.

Also registered as 3 other CAS numbers

719293-04-6 · 1430221-00-3 · 103-90-2

Concern score

60/100High concern based on regulatory listings.

High confidence

Acetaminophen in plain language

What it is: Also known as Paracetamol · 4-Acetamidophenol · Apap · Biocetamol · N-(4-Hydroxyphenyl)acetamide · N-Acetyl-p-aminophenol
Show all 87 names
P-hydroxy-acetanilid · Phenaphen · Vermidon · 4'-Hydroxyacetanilide · 4-(Acetylamino)phenol · 4-(N-Acetylamino)phenol · 4-Acetaminophenol · 4-hydroxyacetanilide · 4′-Hydroxyacetanilide · Acephen · Abensanil · Acamol · Acetagesic · Acetamide, N-(4-hydroxyphenyl)- · Acetaminofen · Algotropyl · Anelix · Butalbital · Dafalgan · Doliprane · Datril · Efferalgan · Injectapap · Lonarid · Neopap · Naprinol · Ofirmev · Panadol · Perfalgan · Tylenol · acetaminophen (tylenol)(4'-hydroxy-acetanilide) 300mg/tablet · acetaminophen (tylenol)(40-hydroxy-acetanilide) · p-Acetamidophenol · p-Hydroxyacetanilide · paracetamol (acetaminophen) · Allay component acetaminophen · Anexsia component acetaminophen · Anoquan component acetaminophen · Bancap component acetaminophen · Bancap hc component acetaminophen · Bucet component acetaminophen · Butapap component acetaminophen · Co-gesic component acetaminophen · Codrix component acetaminophen · Darvocet component acetaminophen · Dhc plus component acetaminophen · Dolene AP-65 component acetaminophen · Drixoral plus component acetaminophen · Duradyne dhc component acetaminophen · Esgic component acetaminophen · Excedrin component acetaminophen · Femcet component acetaminophen · Fioricet component acetaminophen · Hy-phen component acetaminophen · Lorcet-hd component acetaminophen · Lortab component acetaminophen · Medigesic plus component acetaminophen · Norcet component acetaminophen · Norco component acetaminophen · Oxycet component acetaminophen · Percocet component acetaminophen · Phrenilin component acetaminophen · Roxicet component acetaminophen · Roxilox component acetaminophen · Sedapap component acetaminophen · Synalgos-dc-a component acetaminophen · Talacen component acetaminophen · Tencon component acetaminophen · Triad component acetaminophen · Triaprin component acetaminophen · Tycolet component acetaminophen · Tylox component acetaminophen · Ultracet component acetaminophen · Vicodin component acetaminophen · Wygesic component acetaminophen · Zydone component acetaminophen · Combogesic component acetaminophen · Combogesic iv component acetaminophen · Trezix component acetaminophen · Xartemis component acetaminophen · paracetamolum
What it does: Used in cosmetics as a skin-conditioning agent.
Skin conditioning
Conditioner
Stabiliser
Is it a concern?: High concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 78 composition records across product categories including Laboratory supplies, Food and drug, Raw materials.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Acetaminophen appears in these published regulatory listings.

In marketed US drugs

Recorded in these product areas

Found in consumer products
Beauty
Pharma
Food
Industrial

EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
EUEFSAConclusion on Pesticides Peer ReviewPeer review of the pesticide risk assessment of the active substance desmedipham (EFSA)
- Peer review of the pesticide risk assessment of the active substance desmedipham (EFSA)Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 78 composition records across product categories including Laboratory supplies, Food and drug, Raw materials. EPA CPDat classifies this chemical for functional uses including Pharmaceutical, Softener and conditioner, proprietary.
- EPA CPDat observed this chemical in 78 composition records across product categories including Laboratory supplies, Food and drug, Raw materials. EPA CPDat classifies this chemical for functional uses including Pharmaceutical, Softener and conditioner, proprietary.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 3217 active drug products and 3432 total products.
- FDA NDC lists this ingredient in 3217 active drug products and 3432 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.
EFSA
European Food Safety Authority
- Peer review of the pesticide risk assessment of the active substance desmedipham (EFSA)
  2018 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Acetaminophen yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EFSA OpenFoodTox
regulatory · updated 2026-10-04
Open →
EPA Chemical and Products Database
exposure · updated September 2013
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA National Drug Code Directory
regulatory · updated 2029-08-30
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Read →

Openfda substance

drugs-about.com

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often FDA National Drug Code directory has listed Acetaminophen in a product composition. These are source records, not Greenveil catalog products.

Source records

3,432

Typical roles

Skin conditioningConditionerStabiliser

See products using Acetaminophen →

Catalog

Found in these products

Cosmetic and personal-care products that list Acetaminophen are shown first. Their ingredient lists include Acetaminophen; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 47 →Find products without it →