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N-(carboxycarbonyl)glycine

CAS 116998-09-5

Also registered as 4 other CAS numbers

148197-49-3 · 148349-03-5 · 148349-66-0 · 5262-39-5

N-(carboxycarbonyl)glycine chemical structure

Concern score

Not assessed — no hazard data yet.

N-(carboxycarbonyl)glycine in plain language

What it is

On cosmetic ingredient lists it appears as “SH-POLYPEPTIDE-13”.

Also known as SH-POLYPEPTIDE-13 · N-Oxalylglycine · Oxalylglycine · 2-(carboxymethylamino)-2-oxoacetic acid · N-Oxaloglycine · Nog

Show all 16 names

Oxaloglycine n- · 2-((Carboxymethyl)amino)-2-oxoacetic acid · 2-oxo-3-azaglutaric acid · DMOG cpd · Glycine, N-(carboxycarbonyl)- · Oxamic acid, (carboxymethyl)- · Oxaloglycine · UNII-VVW38EB8YS · Undecyl dodecyl phthalate (Technical) · n-oxalyl glycine

What it does

Used in cosmetics as a skin protectant.

  • Skin protecting
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

What we know about this ingredient

EPA DSSTox provides the canonical identifier, structure, and synonym profile for this chemical.

Regulation

No restrictions found. N-(carboxycarbonyl)glycine appears in these published regulatory listings.

  • EUCosIngActivesh-Polypeptide-13 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Noggin Protein used as such or adapted to the production host. It contains a maximum of 232 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.
    • sh-Polypeptide-13 is a single chain synthetic human peptide, produced by fermentation in E. coli. The starting gene is a synthesized copy of the human gene which codes for Noggin Protein used as such or adapted to the production host. It contains a maximum of 232 amino acids which may contain disulfide bonds and/or glycosylation. The protein consists of the proper sequence of the 20 standard amino acids.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for N-(carboxycarbonyl)glycine. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for N-(carboxycarbonyl)glycine yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

5 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.