# Niacinamide

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid2020929
Categories: beauty, cleaning, food, industrial, pharma
Functions: skin conditioning, skin conditioning, Cosmetic Ingredient, Flavouring and nutrient, Humectant, Softener and conditioner
Identifier: AI-0098-92-0

> Niacinamide is used as skin conditioning / skin conditioning. Greenveil chemical-concern score: 25/100 — Minor concern informed by published safety evidence.. Assessed from 2 research documents across 16 sources.

## Safety assessment

- Chemical concern score: 25/100 — Minor concern informed by published safety evidence.
- Confidence: 4
- Rationale: EPA CPDat observed this chemical in 2264 composition records across product categories including Food and drug, Laboratory supplies, Personal care.

## Regulatory status

- AU: Listed — Industrial chemical listed for Australian introduction.
- AU: Permitted — Listed in approved ingredient terminology.
- US: commercial use observed — EPA CPDat observed this chemical in 2264 composition records across product categories including Food and drug, Laboratory supplies, Personal care. EPA CPDat classifies this chemical for functional uses including Humectant, Softener and conditioner, Cosmetic Ingredient.
- US: inactive ingredient database — Route: TOPICAL; Dosage form: CREAM; Potency: NA
- US: inactive ingredient database — Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 25 mg
- US: marketed drug occurrence — FDA NDC lists this ingredient in 190 active drug products and 216 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION; Potency: 2.5 %w/v
- US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION; Potency: 2.5 %w/v

## Linked research

- Open access review of niacinamide formulation use (PMC PMC2000001)
- Topical niacinamide and skin barrier outcomes (PubMed 1000001)

_Assessed by Greenveil._