Food use
Food-use source coverage is present in the current record.
The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.
- beauty
- cleaning
- food
- industrial
Tromethamine
CAS 108195-86-4
Deodorizer · Fragrance · pH regulating agent
Concern score
Not assessed — no hazard data yet.
Why it's flagged
EPA CPDat observed this chemical in 731 composition records across product categories including Food and drug, Laboratory supplies, Cleaning products and household care.
Regulation
No restrictions found. Tromethamine appears in these published regulatory listings.
- commercial_presence
- consumer_product_presence
- cpdat_category:beauty|cleaning|pharma|food|industrial
- currently_marketed_ndc
- definition_level:complete
- definition_type:primary
- inactive_ingredient_database
- ingredient_type:ingredient substance
USFDAinactive ingredient database28 entries — 14 administration routes
- Route: ENDOTRACHEAL; Dosage form: SUSPENSION; Potency: 2.42 mgSource →
- Route: INTRA-ARTERIAL; Dosage form: INJECTION; Maximum daily exposure: 562 mgSource →
- Route: INTRA-ARTERIAL; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 300 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION; Maximum daily exposure: 437 mgSource →
- Route: INTRAMUSCULAR; Dosage form: INJECTION, SOLUTION; Potency: 1.21 %w/vSource →
- Route: INTRATHECAL; Dosage form: SOLUTION; Potency: 0.12 %w/vSource →
- Route: INTRATYMPANIC; Dosage form: SUSPENSION; Maximum daily exposure: 2 mgSource →
- Route: INTRAVASCULAR; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 225 mgSource →
- Route: INTRAVASCULAR; Dosage form: SOLUTION; Potency: 0.12 %w/vSource →
- Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 1134 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SUSPENSION; Potency: 6.06 mgSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Potency: 0.24 %w/vSource →
- Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 300 mgSource →
- Route: INTRAVENOUS; Dosage form: SOLUTION; Potency: 0.12 %w/vSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 0.75 %w/vSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION, GEL FORMING / DROPS; Maximum daily exposure: 1 mgSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION, GEL FORMING, EXTENDED RELEASE; Potency: 0.8 %w/wSource →
- Route: OPHTHALMIC; Dosage form: SOLUTION/ DROPS; Potency: 0.8 %w/vSource →
- Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Potency: ADJ PHSource →
- Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 30 mgSource →
- Route: ORAL; Dosage form: SOLUTION; Potency: 1.21 mg/1mlSource →
- Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 30 mgSource →
- Route: RECTAL; Dosage form: SOLUTION; Potency: 0.12 %w/vSource →
- Route: RESPIRATORY (INHALATION); Dosage form: SOLUTION; Potency: 0.01 %w/vSource →
- Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 56 mgSource →
- Route: TOPICAL; Dosage form: SOLUTION; Potency: 8.4 %w/wSource →
- Route: TRANSDERMAL; Dosage form: GEL; Maximum daily exposure: 10 mgSource →
- Route: URETHRAL; Dosage form: SOLUTION; Potency: 0.12 %w/vSource →
USEPAcommercial use observedEPA CPDat observed this chemical in 731 composition records across product categories including Food and drug, Laboratory supplies, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Deodorizer, pH regulating agent, Fragrance.
- EPA CPDat observed this chemical in 731 composition records across product categories including Food and drug, Laboratory supplies, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Deodorizer, pH regulating agent, Fragrance.Source →
USFDAmarketed drug occurrenceFDA NDC lists this ingredient in 3 active drug products and 5 total products.
- FDA NDC lists this ingredient in 3 active drug products and 5 total products.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →
Evidence
No graded sources yet for Tromethamine. We publish evidence only once a source is linked and reviewed — this ingredient is in the catalog, but has not been assessed.
Allergen profile
Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.
- SoyContains · Oral (ingested)
Source: chemindex_name_match
Suitability
Context-specific fit derived from published classifications and the current ingredient evidence profile.
Good fit
Fragrance avoidance
Not a strong fit for fragrance avoidance because it carries Fragrance.
The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.
Where it appears
Prevalence of Tromethamine in our catalog (epa_cpdat).
Products
731
Brands
6
Food and drugLaboratory suppliesCleaning products and household carePersonal careIndustrial products
Typical roles
DeodorizerFragrancepH regulating agent
Found in these products
- Cicalfate +Avene · Non Food ProductsHigh
- Beauty of Joseon, Relief Sun: Rice + Probiotics, SPF 50+ PA ++++Beauty of Joseon · BeautyLow
- CicalfateAvène · Non Food ProductsCritical
- centella sun creamNon Food ProductsLow
- Beauty of Joseon Revive Eye SerumBeauty
- Crema facial hidrata ácido hialurónico y aloe veraDeliplus · Non Food ProductsMinor
- Cicalfate+ creme reparatrice protectriceAvèneCritical
- Mirabelle sheet maskMinor
- mascaraELFMinor
- Lightweight Daily MoisturizerGood Molecules · Body Moisturizer
- Scent Discovery for Him Must Havesbelk · CologneCritical
- Invictus Parfum 1.5 mlRabanne · ParfumuriHigh
- Clinique Moisture Surge 100H Auto-Replenishing Hydrator 75 mlClinique · BeautyCritical
- sephoraNon Food ProductsCritical
- garniergarnier · SpfMinor
- Hugo Boss Bottled ElixerBoss · PerfumesCritical
- HTH Bodylotion Original 200mlLILLEBORG AS · Non Food Products
- guardian hand cream lovely lavenderGuardian · Cosmetic ProductsHigh
- Earth to skinMinor
- lx platinumModerate
- AlphaRet Overnight Creamskinbe+ter SCIENCE · Face CreamCritical
- razorsrazorsNon Food ProductsModerate
- Håndsåpe Pure Fruity Fresh 300mlElle basic asModerate
- Numbuzin No.3 Super Glowing Essence TonerBeautyHigh
