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Tocopheryl succinate

CAS 53532-12-0 · 20/100 · High conf.

Also registered as 4 other CAS numbers

55134-51-5 · 120246-47-1 · 4345-03-3 · 17407-37-3

Tocopheryl succinate chemical structure

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Tocopheryl succinate in plain language

What it is

Also known as Tocopheryl acid succinate · .alpha.-tocopherol succinate · D-alpha tocoferil acid succinate · Rrr-alpha-tocopheryl acid succinate · D-alpha tocopheryl acid succinate · .alpha.-tocopherol succinate, d-

Show all 29 names

D-alpha-tocopheryl acid succinate · alpha-Tocopherol succinate · d-alpha-Tocopheryl succinate · .alpha.-tocopheryl succinate · .alpha.-tocopheryl succinate, d- · Rrr-.alpha.-tocopheryl hydrogen succinate · Tocopherol succinate · Vitamin e (alpha-tocopheryl succinate) · Vitamin e hemisuccinate · Vitamin e succinate · Vitamine e succinate · (+)-a-tocopherol acid succinate from natural a-tocopherol · (+)-alpha-Tocopheryl succinate · Alpha-tocopherol acid succinate · Alpha-tocopherol succinate, d- · Covitol 1210 · D-alpha-Tocopherol succinate · D-|A-Tocopherol succinate · J24.824J · alpha-Tocopherol hemisuccinate · alpha-Tocopheryl acid succinate · alpha-Vitamin E succinate · d-alpha-Tocopherol acid succinate

What it does

Used in cosmetics as an antioxidant.

  • Antioxidant
  • Flavouring
Is it a concern?
Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 5 composition records across product categories including Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Tocopheryl succinate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • EUCosIngActive.alpha.-Tocopheryl hydrogen succinate
  • EUEFSAEFSA opinionOpinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to D-alpha-tocopheryl acid succinate as a source of vitamin E in foods intended for the general population, food supplements and foods for particular nutritional uses (EFSA AFC)
    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to D-alpha-tocopheryl acid succinate as a source of vitamin E in foods intended for the general population, food supplements and foods for particular nutritional uses (EFSA AFC)Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 5 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Antioxidant, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 5 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Antioxidant, Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to D-alpha-tocopheryl acid succinate as a source of vitamin E in foods intended for the general population, food supplements and foods for particular nutritional uses (EFSA AFC)

      2005 · EU EFSA listing · Read the source →

Evidence & sources

No graded research studies for Tocopheryl succinate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA Chemical and Products Database

    exposure · updated October 2018

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (2)
Openfda substance

nikkajiweb.jst.go.jp

Read →
Openfda substance

dsld.od.nih.gov

Read →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Tocopheryl succinate in a product composition. These are source records, not Greenveil catalog products.

Source records

5

Named organisations

5

Personal care

Typical roles

AntioxidantFlavouring
See products using Tocopheryl succinate →

Catalog

Found in these products

Their ingredient lists include Tocopheryl succinate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 14 →Find products without it →