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Acetyltributyl citrate

CAS 37070-91-0 · 40/100 · High conf.

Also registered as 2 other CAS numbers

791812-73-2 · 77-90-7

Acetyltributyl citrate chemical structure

Concern score

40/100Moderate concern based on regulatory listings.
High confidence

Acetyltributyl citrate in plain language

What it is

On cosmetic ingredient lists it appears as “Acetyl tributyl citrate”.

Also known as Acetyl tributyl citrate · Tributyl acetylcitrate · Tri-n-butyl acetyl citrate · 2-ACETYLTRIBUTYLCITRATE · O-acetyltributyl ester citric acid · Tributyl 2-(acetyloxy)propane-1,2,3-tricarboxylate

Show all 29 names

tributyl 2-acetyloxypropane-1,2,3-tricarboxylate · 1,2,3-propanetricarboxylic acid, 2 · 1,2,3-tributyl 2-(acetyloxy)propane-1,2,3-tricarboxylate · 2-(Acetyloxy)-1,2,3-propanetricarboxylic acid tributyl ester · 2-Acetoxy-1,2,3-propanetricarboxylic acid tributyl ester · 2-acetyl-1,2,3-propane tri carboxylic acid tributyl ester · Atbc · Acetyl butyl citrate · Acetyl tri-n-butyl citrate · Acetyl tributyl citrate (tributyl O-acetyl citrate) · Acetylcitric acid tributyl ester · Acetyltri-n-butyl citrate · Blo-trol · Citric acid, tributyl ester, acetate · Citroflex A · Citroflex A 4 · Tributyl 2-ACETOXYPROPANE-1,2,3-TRICARBOXYLATE · Tributyl 2-(acetyloxy)-1,2,3-propanetricarboxylate · Tributyl 2-acetoxy-1,2,3-propanetricarboxylate · Tributyl acetyl citrate · Tributyl citrate acetate · Tributyl-O-Acetyl citrate · tributyl ester

What it does

Used in cosmetics as a plasticiser and a fragrance ingredient. Acetylcitric acid tributyl ester.

  • Plasticiser
  • Perfuming
  • Fragrance
  • Flavouring agent
  • Film former
  • Solvent
Is it a concern?
Moderate concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 1664 composition records across product categories including Construction and building materials, Personal care, Construction.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Acetyltributyl citrate appears in these published regulatory listings.

  • Inactive ingredient in US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • Cleaning
  • Industrial
  • USFDAinactive ingredient database8 entries — 2 administration routes
    • Route: ORAL; Dosage form: CAPSULE, EXTENDED RELEASE; Maximum daily exposure: 23 mgSource →
    • Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 150 mgSource →
    • Route: ORAL; Dosage form: TABLET, DELAYED RELEASE; Maximum daily exposure: 69 mgSource →
    • Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 309 mgSource →
    • Route: TOPICAL; Dosage form: SOLUTION; Potency: 5.4 %w/wSource →
    • Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 7 mgSource →
    • Route: ORAL; Dosage form: CAPSULE, DELAYED RELEASE; Maximum daily exposure: 122 mgSource →
    • Route: ORAL; Dosage form: CAPSULE, COATED; Maximum daily exposure: 11 mgSource →
  • EUCosIngActiveAcetylcitric acid tributyl ester
  • EUEFSAEFSA opinionOpinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request related to a 10th list of substances for food contact materials (EFSA AFC)
    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request related to a 10th list of substances for food contact materials (EFSA AFC)Source →
  • GLOBALJECFANo safety concern at current levels of intake when used as a flavouring agentJECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.
    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1664 composition records across product categories including Construction and building materials, Personal care, Construction. EPA CPDat classifies this chemical for functional uses including Plasticizer, Deodorizer, Fragrance.
    • EPA CPDat observed this chemical in 1664 composition records across product categories including Construction and building materials, Personal care, Construction. EPA CPDat classifies this chemical for functional uses including Plasticizer, Deodorizer, Fragrance.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) on a request related to a 10th list of substances for food contact materials (EFSA AFC)

      2005 · EU EFSA listing · Read the source →

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

    • JECFA evaluation lists ADI No safety concern at current levels of intake when used as a flavouring agent. Functional class: flavouring agent.

      Year not recorded · GLOBAL JECFA listing · Read the source →

    • JECFA evaluation record.

      Year not recorded · GLOBAL JECFA listing · Read the source →

Evidence & sources

No graded research studies for Acetyltributyl citrate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

9 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated may 17, 2017

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA Inactive Ingredient Database

    regulatory · updated 2026-01-09

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Acetyltributyl citrate in a product composition. These are source records, not Greenveil catalog products.

Source records

1,664

Named organisations

6

Construction and building materialsPersonal careConstructionHome maintenanceFurniture and furnishingsPet and animal care

Typical roles

PlasticiserPerfumingFragranceFlavouring agentFilm formerSolvent
See products using Acetyltributyl citrate →

Catalog

Found in these products

Their ingredient lists include Acetyltributyl citrate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.