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Pramoxine hcl

CAS 637-58-1

Pramoxine hcl chemical structure

Concern score

Not assessed — no hazard data yet.

Pramoxine hcl in plain language

What it is

Also known as Pramoxine hydrochloride · Pramocaine hydrochloride · 4-N-BUTOXYPHENYL.GAMMA.-MORPHOLINOPROPYL ether hydrochloride · Curasore · Dermal-Soothe · Deter-X

Show all 24 names

Honey Pot · Ivy Wash · Poison Ivy Wash · Pramocainhydrochlorid · Pramox-1 · Pramoxine HCI · Pramoxine hydrochloride (USP) · Proctofoam NS · Reeses · Suffusion P · Tronothane · clorhidrato pramocaina · chlorhydrate pramocaine · pramoxine hcl 1% · pramoxine hydrochloride (active ingredient) · Epifoam component pramoxine hydrochloride · Pramosone component pramoxine hydrochloride · Proctofoam hc component pramoxine hydrochloride

What it does

Used in cosmetics as an antioxidant.

  • Antioxidant
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Pramoxine hcl appears in these published regulatory listings.

  • In marketed US drugs

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • USFDAmarketed drug occurrence2 entries
    • FDA NDC lists this ingredient in 2 active drug products and 2 total products.Source →
    • FDA NDC lists this ingredient in 268 active drug products and 284 total products.Source →
  • EUCosIngActiveRestriction: II/405
  • USEPAcommercial use observedEPA CPDat observed this chemical in 5 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Antioxidant.
    • EPA CPDat observed this chemical in 5 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Antioxidant.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Pramoxine hcl. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Pramoxine hcl yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

7 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated october 17, 2014

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA National Drug Code Directory

    regulatory · updated 2027-12-31

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Nothing to weigh for this context yet.

No signal in this context

We have no published hazard signal for this ingredient, so we cannot say how it behaves in this context — that is missing evidence, not a clean result.

Where it has been recorded

How often EPA CPDat has listed Pramoxine hcl in a product composition. These are source records, not Greenveil catalog products.

Source records

5

Named organisations

3

Personal care

Typical roles

Antioxidant
See products using Pramoxine hcl →

Catalog

Found in these products

Their ingredient lists include Pramoxine hcl; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 1 →Find products without it →