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Benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl-

CAS 88-40-4

Benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl- chemical structure

Concern score

Not assessed — no hazard data yet.

Benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl- in plain language

What it is

On cosmetic ingredient lists it appears as “2-TERT-BUTYL-5-METHYLANISOLE”.

Also known as 2-TERT-BUTYL-5-METHYLANISOLE · 6-TERT-BUTYL-3-METHYLANISOLE · 1-tert-Butyl-2-methoxy-4-methylbenzene · 1-(1,1-DIMETHYLETHYL)-2-METHOXY-4-METHYLBENZENE · 1-tert-butyl-2-methoxy-4-methyl-benzene · 2-tert-butyl-5-methyl anisole

Show all 12 names

4-TERT-BUTYL-3-METHOXYTOLUENE · Anisole, 2-TERT-BUTYL-5-METHYL- · InChI=1/C12H18O/c1-9-6-7-10(12(2,3)4)11(8-9)13-5/h6-8H,1-5H3 · Nfdfefjtyrahem-uhfffaoysa- · Nfdfefjtyrahem-uhfffaoysa-n · UNII-PZP00ZS37E

What it does

Used in cosmetics as a fragrance ingredient.

  • Perfuming
  • Fragrance
Is it a concern?
We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl- appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Industrial
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Fragrance.
    • EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Fragrance.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl-. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

Evidence & sources

No graded research studies for Benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl- yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EPA Chemical and Products Database

    exposure · updated 2019-12-20

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl- in a product composition. These are source records, not Greenveil catalog products.

Named organisations

1

Typical roles

PerfumingFragrance
See products using Benzene, 1-(1,1-dimethylethyl)-2-methoxy-4-methyl- →