Skip to content
  • beauty
  • food

Musk

CAS 17598-28-6 · 60/100 · High conf.

Also registered as 1 other CAS number

123-69-3

Musk chemical structure

Concern score

60/100High concern based on regulatory listings.
High confidence

Musk in plain language

What it is

On cosmetic ingredient lists it appears as “HEXADEC-7-EN-16-OLIDE”.

Also known as HEXADEC-7-EN-16-OLIDE · Ambrettolide · Hexadec-7-en-1,16-lactone · OXACYCLOHEPTADEC-8-EN-2-ONE, (8Z)- · (8Z)-1-Oxacycloheptadec-8-en-2-one · 16-HYDROXY-7-HEXADECENOIC acid lactone

Show all 19 names

7-HEXADECEN-16-OLIDE, (z)- · Ambrette musk · Ambrettolid · Natural musk ambrette · (8Z)-Oxacycloheptadec-8-en-2-one · (Z)-7-Hexadecen-1,16-olide · (Z)-7-Hexadecen-16-olide · (Z)-Oxacycloheptadec-8-en-2-one · 16-hydroxy-7-hexadecenoic acid, omicron-lactone · Musk ambrette (natural) · Musk natural · OXACYCLOHEPTADEC-8-EN-2-ONE, (z)- · Oxacycloheptadec-8-en-2-one

What it does

Used in cosmetics as a fragrance ingredient.

  • Perfuming
  • Fragrance
  • Flavouring
Is it a concern?
High concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 1 composition records across product categories including Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Musk appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • EUEFSAEFSA opinion2 entries
    • Scientific Opinion on Flavouring Group Evaluation 10, Revision 3 (FGE.10Rev3): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 (EFSA CEF)Source →
    • Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 (EFSA CEF)Source →
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 1 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.
    • EPA CPDat observed this chemical in 1 composition records across product categories including Personal care. EPA CPDat classifies this chemical for functional uses including Fragrance, Flavouring and nutrient.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Scientific Opinion on Flavouring Group Evaluation 10, Revision 3 (FGE.10Rev3): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 (EFSA CEF)

      2012 · EU EFSA listing · Read the source →

    • Scientific Opinion on Flavouring Group Evaluation 10, Revision 2 (FGE.10Rev2): Aliphatic primary and secondary saturated and unsaturated alcohols, aldehydes, acetals, carboxylic acids and esters containing an additional oxygenated functional group and lactones from chemical groups 9, 13 and 30 (EFSA CEF)

      2011 · EU EFSA listing · Read the source →

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

Evidence & sources

No graded research studies for Musk yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →
  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →
  • EPA Chemical and Products Database

    exposure · updated September 2013

    Open →
  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →
  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →
  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →
  • openFDA Substance

    registry · updated 2026-05-24

    Open →
  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Musk in a product composition. These are source records, not Greenveil catalog products.

Source records

1

Named organisations

3

Personal care

Typical roles

PerfumingFragranceFlavouring
See products using Musk →

Catalog

Found in these products

Cosmetic and personal-care products that list Musk are shown first. Their ingredient lists include Musk; each product's own rating depends on its whole formula, so it is shown on the product page, not here.