What does Trisodium glycyrrhizate do?

Used in cosmetics as a skin-conditioning agent and a fragrance ingredient.

Is Trisodium glycyrrhizate safe?

We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

beauty
industrial

Trisodium glycyrrhizate

CAS 56649-78-6

Also registered as 1 other CAS number

71277-78-6

Trisodium glycyrrhizate chemical structure

Concern score

Not assessed — no hazard data yet.

Trisodium glycyrrhizate in plain language

What it is: Also known as Trisodium glycyrrhizinate · Glycyrrhizic acid trisodium salt · Ccxaylqlolxxke-dwjagbrcsa-k · FT41834 · G0217 · Glycyrrhizin Trisodium Salt
Show all 12 names
Oristar tsg · Q27262938 · Trisodium glycyrrhizate vinyals · Trisodium Glycyrrhizinate Hydrate · Trisodium glycyrrhizin · UNII-5VWB9ZP8JV
What it does: Used in cosmetics as a skin-conditioning agent and a fragrance ingredient.
Skin conditioning
Fragrance
Conditioner
Deodorant
Is it a concern?: We haven't assessed a concern score for this ingredient yet. It is listed for cosmetic use in the EU.

Regulation

No restrictions found. Trisodium glycyrrhizate appears in these published regulatory listings.

Recorded in these product areas

Found in consumer products
Industrial

EUCosIngActiveListed in CosIng inventory for cosmetic use.
- Listed in CosIng inventory for cosmetic use.Source →
USEPAcommercial use observedEPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Deodorizer, Softener and conditioner.
- EPA CPDat observed this chemical in 0 composition records across product categories including unclassified products. EPA CPDat classifies this chemical for functional uses including Deodorizer, Softener and conditioner.Source →
USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
- openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

No expert opinion on file for Trisodium glycyrrhizate. These are the independent scientific bodies that assess ingredients like this one; we show an opinion only when a record we hold cites it.

SCCS
EU Scientific Committee on Consumer Safety
No SCCS opinion on file.
CIR
Cosmetic Ingredient Review (US expert panel)
No CIR safety assessment on file.

Evidence & sources

No graded research studies for Trisodium glycyrrhizate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

6 data sources

Where this comes from

CosIng
regulatory · updated 2026-09-23
Open →
EPA Chemical and Products Database
exposure · updated 2019-12-20
Open →
EPA DSSTox Identifiers
chemistry · updated 2025-12-29
Open →
FDA GSRS UNII
registry · updated 2026-02-26
Open →
openFDA Substance
registry · updated 2026-05-24
Open →
PubChem Live Enrichment
chemistry · updated 2026-05-17
Open →

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Fragrance avoidance

Not a strong fit for fragrance avoidance because it carries Fragrance.

Avoid

The ingredient itself is a fragrance-linked signal, so it is better treated as an avoid case when fragrance exposure is the main concern.

Where it has been recorded

How often EPA CPDat has listed Trisodium glycyrrhizate in a product composition. These are source records, not Greenveil catalog products.

Named organisations

Typical roles

Skin conditioningFragranceConditionerDeodorant

See products using Trisodium glycyrrhizate →