# ANHYDROUS CITRIC ACID

URL: https://app.greenveil.ai/ingredients/ingredient_dtxsid_dtxsid3020332
Categories: beauty, cleaning, food, industrial, pharma
Functions: chelating agent, acidity regulator, acidity regulator, acidity regulator, Biocide, Chelating agent, Cleaning agent, Cosmetics, Deodorizer, Flavouring and nutrient, Fragrance, Iron Control, Preservative, Stabilizing agent, pH regulating agent, topical treatment
Identifier: DTXSID3020332

> ANHYDROUS CITRIC ACID is used as chelating agent / acidity regulator. Greenveil chemical-concern score: 25/100 — Minor concern based on regulatory listings.. Assessed from 71 sources.

## Safety assessment

- Chemical concern score: 25/100 — Minor concern based on regulatory listings.
- Confidence: 4
- Rationale: EPA CPDat observed this chemical in 20925 composition records across product categories including Construction and building materials, Laboratory supplies, Cleaning products and household care.

## Regulatory status

- AU: Permitted — Permitted food additive under the Food Standards Code.
- EU: Evaluated — EFSA OpenFoodTox includes 1 reference value for this substance.
- US: commercial use observed — EPA CPDat observed this chemical in 20925 composition records across product categories including Construction and building materials, Laboratory supplies, Cleaning products and household care. EPA CPDat classifies this chemical for functional uses including Chelating agent, pH regulating agent, Preservative.
- US: inactive ingredient database — Route: BUCCAL; Dosage form: FILM, SOLUBLE; Maximum daily exposure: 2 mg
- US: inactive ingredient database — Route: BUCCAL; Dosage form: TABLET; Maximum daily exposure: 30 mg
- US: inactive ingredient database — Route: INTRACARDIAC; Dosage form: INJECTION; Maximum daily exposure: 25 mg
- US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION; Maximum daily exposure: 101 mg
- US: inactive ingredient database — Route: INTRAMUSCULAR; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 25 mg
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: CONCENTRATE; Potency: ADJ PH
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION; Maximum daily exposure: 1152 mg
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, FOR SOLUTION; Maximum daily exposure: 35 mg
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, POWDER, LYOPHILIZED, FOR SOLUTION; Maximum daily exposure: 414 mg
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 540 mg
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: INJECTION, SOLUTION, CONCENTRATE; Maximum daily exposure: 81 mg
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: LIQUID; Maximum daily exposure: 18 mg
- US: inactive ingredient database — Route: INTRAVENOUS; Dosage form: SOLUTION, CONCENTRATE; Maximum daily exposure: 60 mg
- US: inactive ingredient database — Route: NASAL; Dosage form: SPRAY; Maximum daily exposure: 5 mg
- US: inactive ingredient database — Route: NASAL; Dosage form: SPRAY, METERED; Maximum daily exposure: 1 mg
- US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SOLUTION; Potency: 0.09 %w/v
- US: inactive ingredient database — Route: OPHTHALMIC; Dosage form: SUSPENSION/ DROPS; Potency: 0.05 %w/v
- US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE; Maximum daily exposure: 131 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: CAPSULE, LIQUID FILLED; Maximum daily exposure: 360 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: CONCENTRATE; Maximum daily exposure: 84 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: ELIXIR; Maximum daily exposure: 90 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: FILM, SOLUBLE; Maximum daily exposure: 7 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: GRANULE, FOR SUSPENSION; Maximum daily exposure: 30 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: PASTE; Maximum daily exposure: 26 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: POWDER, FOR SOLUTION; Maximum daily exposure: 123 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: POWDER, FOR SUSPENSION; Maximum daily exposure: 570 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: SOLUTION; Maximum daily exposure: 3900 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: SUSPENSION; Maximum daily exposure: 400 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: SUSPENSION, EXTENDED RELEASE; Maximum daily exposure: 62 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: SUSPENSION/ DROPS; Maximum daily exposure: 15 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: SYRUP; Maximum daily exposure: 268 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: TABLET; Maximum daily exposure: 197 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, CHEWABLE; Maximum daily exposure: 4 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, CHEWABLE, EXTENDED RELEASE; Maximum daily exposure: 12 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, EFFERVESCENT; Maximum daily exposure: 840 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, EXTENDED RELEASE; Maximum daily exposure: 312 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Maximum daily exposure: 46 mg
- US: inactive ingredient database — Route: ORAL; Dosage form: TABLET, ORALLY DISINTEGRATING, DELAYED RELEASE; Maximum daily exposure: 48 mg
- US: inactive ingredient database — Route: RECTAL; Dosage form: SUSPENSION; Maximum daily exposure: 904 mg
- US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: SOLUTION; Maximum daily exposure: 5 mg
- US: inactive ingredient database — Route: RESPIRATORY (INHALATION); Dosage form: SUSPENSION; Maximum daily exposure: 1 mg
- US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION; Maximum daily exposure: 101 mg
- US: inactive ingredient database — Route: SUBCUTANEOUS; Dosage form: INJECTION, SOLUTION; Maximum daily exposure: 25 mg
- US: inactive ingredient database — Route: SUBLINGUAL; Dosage form: FILM; Maximum daily exposure: 11 mg
- US: inactive ingredient database — Route: SUBLINGUAL; Dosage form: TABLET; Maximum daily exposure: 36 mg
- US: inactive ingredient database — Route: SUBLINGUAL; Dosage form: TABLET, ORALLY DISINTEGRATING; Potency: ADJ PH
- US: inactive ingredient database — Route: TOPICAL; Dosage form: AEROSOL; Potency: 0.08 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: AEROSOL, FOAM; Maximum daily exposure: 6 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: CLOTH; Potency: 4.2 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: CREAM; Maximum daily exposure: 1 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: GEL; Maximum daily exposure: 3 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: LOTION; Maximum daily exposure: 211 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: OIL; Maximum daily exposure: 2 mg
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SHAMPOO; Potency: 0.07 %w/w
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SPRAY; Potency: 0.01 %w/w
- US: inactive ingredient database — Route: TRANSMUCOSAL; Dosage form: LOZENGE; Maximum daily exposure: 44 mg
- US: marketed drug occurrence — FDA NDC lists this ingredient in 75 active drug products and 104 total products.
- US: listed in openFDA substance — openFDA substance registry classifies this ingredient as chemical.
- US: Allowed — Substance added to food inventory includes citric acid.
- US: inactive ingredient database — Route: TOPICAL; Dosage form: SOLUTION; Potency: 4.35 %w/v
- US: inactive ingredient database — Route: AURICULAR (OTIC); Dosage form: SOLUTION/ DROPS; Maximum daily exposure: 1 mg
- US: inactive ingredient database — Route: BUCCAL; Dosage form: FILM; Maximum daily exposure: 9 mg
- US: observed in branded food ingredient statements — Observed in 9 USDA branded foods including 1 LITER BOTTLE BLACKCHERRY, 1 LITER BOTTLE DIET BLACK CHERRY, 1 LITER BOTTLE TOM COLLINS.

_Assessed by Greenveil._