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Sucrose acetate isobutyrate

CAS 27216-37-1 · 20/100 · High conf.

Also registered as 2 other CAS numbers

1338-47-2 · 126-13-6

Sucrose acetate isobutyrate chemical structure

Concern score

20/100Minor concern based on regulatory listings.
High confidence

Sucrose acetate isobutyrate in plain language

What it is

Also known as Sucrose diacetate hexaisobutyrate · Saib · Saccharose acetate isobutyrate · E-444 · E444 · Isobutyric acid, hexaester with sucrose diacetate

Show all 18 names

Sucrose acetate isobutanoate · Sucrose acetate isobutylate · Di(acetate)-hexaisobutyrate de saccharose · Ins NO.444 · INS-444 · Methylpropanoate · Saib 100S · Sucrose acetoisobutyrate · Sucrose di(acetate) hexaisobutyrate · diacetate hexaisobutyrate Sucrose · UNII-H5KI1C3YTV · di(acetato)-hexaisobutirato de sacarosa

What it does

Used in cosmetics as a film former and a plasticiser.

  • Film forming
  • Plasticiser
  • Film former
  • Solvent
  • Flavouring
Is it a concern?
Minor concern: no hazard classifications on record. It is listed for cosmetic use in the EU.

Why it's flagged

EPA CPDat observed this chemical in 2 composition records across product categories including Construction and building materials, Personal care.

The score describes this ingredient's chemical identity — its hazard profile from published classifications and regulatory status — not the safety of any product it appears in.

Regulation

No restrictions found. Sucrose acetate isobutyrate appears in these published regulatory listings.

Recorded in these product areas

  • Found in consumer products
  • Beauty
  • EUCosIngActiveListed in CosIng inventory for cosmetic use.
    • Listed in CosIng inventory for cosmetic use.Source →
  • EUEFSAEFSA opinionRe-evaluation of sucrose acetate isobutyrate (E 444) as a food additive (EFSA ANS)
    • Re-evaluation of sucrose acetate isobutyrate (E 444) as a food additive (EFSA ANS)Source →
  • GLOBALJECFAEvaluatedJECFA evaluation record.
  • USEPAcommercial use observedEPA CPDat observed this chemical in 2 composition records across product categories including Construction and building materials, Personal care. EPA CPDat classifies this chemical for functional uses including Film former, Plasticizer, Solvent.
    • EPA CPDat observed this chemical in 2 composition records across product categories including Construction and building materials, Personal care. EPA CPDat classifies this chemical for functional uses including Film former, Plasticizer, Solvent.Source →
  • USFDAlisted in openFDA substanceopenFDA substance registry classifies this ingredient as chemical.
    • openFDA substance registry classifies this ingredient as chemical.Source →

Expert safety opinions

Independent scientific assessments cited by the records we hold, with the year and link where the record gives one.

  • SCCS

    EU Scientific Committee on Consumer Safety

    No SCCS opinion on file.

  • CIR

    Cosmetic Ingredient Review (US expert panel)

    No CIR safety assessment on file.

  • EFSA

    European Food Safety Authority

    • Re-evaluation of sucrose acetate isobutyrate (E 444) as a food additive (EFSA ANS)

      2016 · EU EFSA listing · Read the source →

  • JECFA

    Joint FAO/WHO Expert Committee on Food Additives

Evidence & sources

No graded research studies for Sucrose acetate isobutyrate yet. This record is compiled from the published data sources below — registries and regulatory listings, not study findings.

8 data sources

Where this comes from

  • CosIng

    regulatory · updated 2026-09-23

    Open →

  • EFSA OpenFoodTox

    regulatory · updated 2026-10-04

    Open →

  • EPA Chemical and Products Database

    exposure · updated February 8, 2019

    Open →

  • EPA DSSTox Identifiers

    chemistry · updated 2025-12-29

    Open →

  • FDA GSRS UNII

    registry · updated 2026-02-26

    Open →

  • WHO JECFA Database

    regulatory · updated 2026-10-04

    Open →

  • openFDA Substance

    registry · updated 2026-05-24

    Open →

  • PubChem Live Enrichment

    chemistry · updated 2026-05-17

    Open →
Reference links (1)
Openfda substance

codexalimentarius.net

Read →

Allergen profile

Canonical allergen markers detected on this ingredient. Each row is derived from the ingredient’s name or synonyms matching a known allergen class — useful when scanning a label for a specific allergy context.

  • SoyContains · Oral (ingested)

    Source: chemindex_name_match

Suitability

Context-specific fit derived from published classifications and the current ingredient evidence profile.

Food use

Food-use source coverage is present in the current record.

Good fit

The ingredient appears in food-oriented source coverage or allowed-use references, which makes food use easier to support than a context with no domain signal at all.

Fragrance avoidance

No fragrance-linked caution surfaced in the current profile.

Good fit

This ingredient does not currently read as a fragrance-linked driver in the published evidence and hazard profile.

Where it has been recorded

How often EPA CPDat has listed Sucrose acetate isobutyrate in a product composition. These are source records, not Greenveil catalog products.

Source records

2

Named organisations

3

Construction and building materialsPersonal care

Typical roles

Film formingPlasticiserFilm formerSolventFlavouring
See products using Sucrose acetate isobutyrate →

Catalog

Found in these products

Their ingredient lists include Sucrose acetate isobutyrate; each product's own rating depends on its whole formula, so it is shown on the product page, not here.

See all 67 →Find products without it →